Remodeling of Aorta Extracellular Matrix as a Result of Transient High Oxygen Exposure in Newborn Rats: Implication for Arterial Rigidity and Hypertension Risk

Fanny Huyard; Catherine Yzydorczyk; Michele M. Castro; Anik Cloutier; Mariane Bertagnolli; Hervé Sartelet; Nathalie Germain; Blandine Comte; Richard Schulz; Denis DeBlois; Anne Monique Nuyt

doi:10.1371/journal.pone.0092287

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Open Access

Peer-reviewed

Research Article

Remodeling of Aorta Extracellular Matrix as a Result of Transient High Oxygen Exposure in Newborn Rats: Implication for Arterial Rigidity and Hypertension Risk

Fanny Huyard ,

Contributed equally to this work with: Fanny Huyard, Catherine Yzydorczyk

Affiliation Sainte-Justine University Hospital Research Center, Department of Paediatrics, Université de Montréal, Montreal, Québec, Canada
⨯
Catherine Yzydorczyk ,

Contributed equally to this work with: Fanny Huyard, Catherine Yzydorczyk

Affiliation Sainte-Justine University Hospital Research Center, Department of Paediatrics, Université de Montréal, Montreal, Québec, Canada
⨯
Michele M. Castro,

Current address: Department of Pharmacology, Faculty of Medicine, University of São Paulo, Ribeirão Preto, Brazil

Affiliation Departments of Pediatrics & Pharmacology, Cardiovascular Research Centre, University of Alberta, Edmonton, Alberta, Canada
⨯
Anik Cloutier,

Affiliation Sainte-Justine University Hospital Research Center, Department of Paediatrics, Université de Montréal, Montreal, Québec, Canada
⨯
Mariane Bertagnolli,

Affiliation Sainte-Justine University Hospital Research Center, Department of Paediatrics, Université de Montréal, Montreal, Québec, Canada
⨯
Hervé Sartelet,

Affiliation Sainte-Justine University Hospital Research Center, Department of Pathology, Université de Montréal, Montreal, Québec, Canada
⨯
Nathalie Germain,

Affiliation Sainte-Justine University Hospital Research Center, Department of Paediatrics, Université de Montréal, Montreal, Québec, Canada
⨯
Blandine Comte,

Affiliation Unit of Human Nutrition UMR 1019, INRA, Research Centre of Clermont-Ferrand/Theix, Saint-Genès-Champanelle, France
⨯
Richard Schulz,

Affiliation Departments of Pediatrics & Pharmacology, Cardiovascular Research Centre, University of Alberta, Edmonton, Alberta, Canada
⨯
Denis DeBlois,

Affiliation Faculty of Pharmacy, Université de Montréal, Montreal, Quebec, Canada
⨯
Anne Monique Nuyt

* E-mail: anne-monique.nuyt@recherche-ste-justine.qc.ca

Affiliation Sainte-Justine University Hospital Research Center, Department of Paediatrics, Université de Montréal, Montreal, Québec, Canada
⨯

Remodeling of Aorta Extracellular Matrix as a Result of Transient High Oxygen Exposure in Newborn Rats: Implication for Arterial Rigidity and Hypertension Risk

Fanny Huyard,
Catherine Yzydorczyk,
Michele M. Castro,
Anik Cloutier,
Mariane Bertagnolli,
Hervé Sartelet,
Nathalie Germain,
Blandine Comte,
Richard Schulz,
Denis DeBlois

Published: April 17, 2014
https://doi.org/10.1371/journal.pone.0092287

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