Rifampicin Protects PC12 Cells from Rotenone-Induced Cytotoxicity by Activating GRP78 via PERK-eIF2α-ATF4 Pathway

Xiuna Jing; Qiaoyun Shi; Wei Bi; Zhifen Zeng; Yanran Liang; Xia Wu; Songhua Xiao; Jun Liu; Lianhong Yang; Enxiang Tao

doi:10.1371/journal.pone.0092110

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Open Access

Peer-reviewed

Research Article

Rifampicin Protects PC12 Cells from Rotenone-Induced Cytotoxicity by Activating GRP78 via PERK-eIF2α-ATF4 Pathway

Xiuna Jing ,

Contributed equally to this work with: Xiuna Jing, Qiaoyun Shi, Wei Bi

Affiliation Department of Neurology, Sun Yat-sen Memorial Hospital of Sun Yat-sen University, Guangzhou, People's Republic of China
⨯
Qiaoyun Shi ,

Contributed equally to this work with: Xiuna Jing, Qiaoyun Shi, Wei Bi

Affiliation Department of Radiology, School of Medicine, Stanford University, Stanford, California, United States of America
⨯
Wei Bi ,

Contributed equally to this work with: Xiuna Jing, Qiaoyun Shi, Wei Bi

Affiliations Department of Neurology, Sun Yat-sen Memorial Hospital of Sun Yat-sen University, Guangzhou, People's Republic of China, Department of Neurology, the First Affiliated Hospital of Jinan University, Guangzhou, People's Republic of China
⨯
Zhifen Zeng,

Affiliation Department of Neurology, Sun Yat-sen Memorial Hospital of Sun Yat-sen University, Guangzhou, People's Republic of China
⨯
Yanran Liang,

Affiliation Department of Neurology, Sun Yat-sen Memorial Hospital of Sun Yat-sen University, Guangzhou, People's Republic of China
⨯
Xia Wu,

Affiliation Department of Neurology, Sun Yat-sen Memorial Hospital of Sun Yat-sen University, Guangzhou, People's Republic of China
⨯
Songhua Xiao,

Affiliation Department of Neurology, Sun Yat-sen Memorial Hospital of Sun Yat-sen University, Guangzhou, People's Republic of China
⨯
Jun Liu,

Affiliation Department of Neurology, Sun Yat-sen Memorial Hospital of Sun Yat-sen University, Guangzhou, People's Republic of China
⨯
Lianhong Yang,

Affiliation Department of Neurology, Sun Yat-sen Memorial Hospital of Sun Yat-sen University, Guangzhou, People's Republic of China
⨯
Enxiang Tao

* E-mail: taoenxiang@163.com

Affiliation Department of Neurology, Sun Yat-sen Memorial Hospital of Sun Yat-sen University, Guangzhou, People's Republic of China
⨯

Rifampicin Protects PC12 Cells from Rotenone-Induced Cytotoxicity by Activating GRP78 via PERK-eIF2α-ATF4 Pathway

Xiuna Jing,
Qiaoyun Shi,
Wei Bi,
Zhifen Zeng,
Yanran Liang,
Xia Wu,
Songhua Xiao,
Jun Liu,
Lianhong Yang,
Enxiang Tao

Published: March 17, 2014
https://doi.org/10.1371/journal.pone.0092110

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