Human Beta-Defensin-1 Suppresses Tumor Migration and Invasion and Is an Independent Predictor for Survival of Oral Squamous Cell Carcinoma Patients

Qi Han; Ruinan Wang; Chongkui Sun; Xin Jin; Dongjuan Liu; Xin Zhao; Lili Wang; Ning Ji; Jing Li; Yu Zhou; Ling Ye; Xinhua Liang; Lu Jiang; Ga Liao; Hongxia Dan; Xin Zeng; Qianming Chen

doi:10.1371/journal.pone.0091867

Loading metrics

Open Access

Peer-reviewed

Research Article

Human Beta-Defensin-1 Suppresses Tumor Migration and Invasion and Is an Independent Predictor for Survival of Oral Squamous Cell Carcinoma Patients

Qi Han ,

Contributed equally to this work with: Qi Han, Ruinan Wang

Affiliation State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China
⨯
Ruinan Wang ,

Contributed equally to this work with: Qi Han, Ruinan Wang

Affiliation State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China
⨯
Chongkui Sun,

Affiliation State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China
⨯
Xin Jin,

Affiliation State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China
⨯
Dongjuan Liu,

Affiliation State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China
⨯
Xin Zhao,

Affiliation State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China
⨯
Lili Wang,

Affiliation State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China
⨯
Ning Ji,

Affiliation State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China
⨯
Jing Li,

Affiliation State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China
⨯
Yu Zhou,

Affiliation State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China
⨯
Ling Ye,

Affiliation State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China
⨯
Xinhua Liang,

Affiliation State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China
⨯
Lu Jiang,

Affiliation State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China
⨯
Ga Liao,

Affiliation State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China
⨯
Hongxia Dan ,

* E-mail: hxdan@foxmail.com (HD); zengxin22@163.com (X. Zeng)

Affiliation State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China
⨯
Xin Zeng ,

* E-mail: hxdan@foxmail.com (HD); zengxin22@163.com (X. Zeng)

Affiliation State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China
⨯
[ ... ],
Qianming Chen

Affiliation State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China
⨯
[ view all ]
[ view less ]

Human Beta-Defensin-1 Suppresses Tumor Migration and Invasion and Is an Independent Predictor for Survival of Oral Squamous Cell Carcinoma Patients

Qi Han,
Ruinan Wang,
Chongkui Sun,
Xin Jin,
Dongjuan Liu,
Xin Zhao,
Lili Wang,
Ning Ji,
Jing Li,
Yu Zhou

Published: March 21, 2014
https://doi.org/10.1371/journal.pone.0091867

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Apoptosis
Is the Subject Area "Apoptosis" applicable to this article?

Thanks for your feedback.
Prostate cancer
Is the Subject Area "Prostate cancer" applicable to this article?

Thanks for your feedback.
Cancers and neoplasms
Is the Subject Area "Cancers and neoplasms" applicable to this article?

Thanks for your feedback.
Cell staining
Is the Subject Area "Cell staining" applicable to this article?

Thanks for your feedback.
Metastasis
Is the Subject Area "Metastasis" applicable to this article?

Thanks for your feedback.
Renal cancer
Is the Subject Area "Renal cancer" applicable to this article?

Thanks for your feedback.
Malignant tumors
Is the Subject Area "Malignant tumors" applicable to this article?

Thanks for your feedback.
Protein expression
Is the Subject Area "Protein expression" applicable to this article?

Thanks for your feedback.