Pro-Inflammatory Chemokine CCL2 (MCP-1) Promotes Healing in Diabetic Wounds by Restoring the Macrophage Response

Stephen Wood; Vijayakumar Jayaraman; Erica J. Huelsmann; Brian Bonish; Derick Burgad; Gayathri Sivaramakrishnan; Shanshan Qin; Luisa A. DiPietro; Andrew Zloza; Chunxiang Zhang; Sasha H. Shafikhani

doi:10.1371/journal.pone.0091574

Loading metrics

Open Access

Peer-reviewed

Research Article

Pro-Inflammatory Chemokine CCL2 (MCP-1) Promotes Healing in Diabetic Wounds by Restoring the Macrophage Response

Stephen Wood,

Affiliation Department of Immunology/Microbiology, Rush University Medical Center, Chicago, Illinois, United States of America
⨯
Vijayakumar Jayaraman,

Affiliation Department of Immunology/Microbiology, Rush University Medical Center, Chicago, Illinois, United States of America
⨯
Erica J. Huelsmann,

Affiliations Department of Immunology/Microbiology, Rush University Medical Center, Chicago, Illinois, United States of America, Rush University Cancer Center, Rush University Medical Center, Chicago, Illinois, United States of America, Developmental Center for AIDS Research, Rush University Medical Center, Chicago, Illinois, United States of America
⨯
Brian Bonish,

Affiliations Department of Immunology/Microbiology, Rush University Medical Center, Chicago, Illinois, United States of America, Department of Dermatology, Rush University Medical Center, Chicago, Illinois, United States of America
⨯
Derick Burgad,

Affiliation Department of Immunology/Microbiology, Rush University Medical Center, Chicago, Illinois, United States of America
⨯
Gayathri Sivaramakrishnan,

Affiliation Department of Immunology/Microbiology, Rush University Medical Center, Chicago, Illinois, United States of America
⨯
Shanshan Qin,

Affiliation Department of Pharmacology, Rush University Medical Center, Chicago, Illinois, United States of America
⨯
Luisa A. DiPietro,

Affiliation Center for Wound Healing and Tissue Regeneration, College of Dentistry, University of Illinois at Chicago, Chicago, Illinois, United States of America
⨯
Andrew Zloza,

Affiliations Department of Immunology/Microbiology, Rush University Medical Center, Chicago, Illinois, United States of America, Rush University Cancer Center, Rush University Medical Center, Chicago, Illinois, United States of America, Developmental Center for AIDS Research, Rush University Medical Center, Chicago, Illinois, United States of America
⨯
Chunxiang Zhang,

Affiliation Department of Pharmacology, Rush University Medical Center, Chicago, Illinois, United States of America
⨯
Sasha H. Shafikhani

* E-mail: Sasha_Shafikhani@rush.edu

Affiliations Department of Immunology/Microbiology, Rush University Medical Center, Chicago, Illinois, United States of America, Rush University Cancer Center, Rush University Medical Center, Chicago, Illinois, United States of America
⨯

Pro-Inflammatory Chemokine CCL2 (MCP-1) Promotes Healing in Diabetic Wounds by Restoring the Macrophage Response

Stephen Wood,
Vijayakumar Jayaraman,
Erica J. Huelsmann,
Brian Bonish,
Derick Burgad,
Gayathri Sivaramakrishnan,
Shanshan Qin,
Luisa A. DiPietro,
Andrew Zloza,
Chunxiang Zhang

Published: March 11, 2014
https://doi.org/10.1371/journal.pone.0091574

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Diabetes mellitus
Is the Subject Area "Diabetes mellitus" applicable to this article?

Thanks for your feedback.
Macrophages
Is the Subject Area "Macrophages" applicable to this article?

Thanks for your feedback.
Wound healing
Is the Subject Area "Wound healing" applicable to this article?

Thanks for your feedback.
Chemokines
Is the Subject Area "Chemokines" applicable to this article?

Thanks for your feedback.
Inflammation
Is the Subject Area "Inflammation" applicable to this article?

Thanks for your feedback.
White blood cells
Is the Subject Area "White blood cells" applicable to this article?

Thanks for your feedback.
Skin tissue
Is the Subject Area "Skin tissue" applicable to this article?

Thanks for your feedback.
Mouse models
Is the Subject Area "Mouse models" applicable to this article?

Thanks for your feedback.