Transcript Analysis Reveals a Specific HOX Signature Associated with Positional Identity of Human Endothelial Cells

Mark Toshner; Benjamin J. Dunmore; Eoin F. McKinney; Mark Southwood; Paola Caruso; Paul D. Upton; John P. Waters; Mark L. Ormiston; Jeremy N. Skepper; Gerard Nash; Amer A. Rana; Nicholas W. Morrell

doi:10.1371/journal.pone.0091334

Loading metrics

Open Access

Peer-reviewed

Research Article

Transcript Analysis Reveals a Specific HOX Signature Associated with Positional Identity of Human Endothelial Cells

Mark Toshner,

Affiliations Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom, Papworth Hospital, Cambridge, United Kingdom
⨯
Benjamin J. Dunmore,

Affiliation Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom
⨯
Eoin F. McKinney,

Affiliation Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom
⨯
Mark Southwood,

Affiliation Papworth Hospital, Cambridge, United Kingdom
⨯
Paola Caruso,

Affiliation Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom
⨯
Paul D. Upton,

Affiliation Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom
⨯
John P. Waters,

Affiliation Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom
⨯
Mark L. Ormiston,

Affiliation Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom
⨯
Jeremy N. Skepper,

Affiliation Department of Physiology and Neuroscience, University of Cambridge, Cambridge, United Kingdom
⨯
Gerard Nash,

Affiliation School of Clinical and Experimental Medicine, Birmingham University, Birmingham, United Kingdom
⨯
Amer A. Rana,

Affiliation Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom
⨯
Nicholas W. Morrell

* E-mail: nwm23@cam.ac.uk

Affiliation Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom
⨯

Transcript Analysis Reveals a Specific HOX Signature Associated with Positional Identity of Human Endothelial Cells

Mark Toshner,
Benjamin J. Dunmore,
Eoin F. McKinney,
Mark Southwood,
Paola Caruso,
Paul D. Upton,
John P. Waters,
Mark L. Ormiston,
Jeremy N. Skepper,
Gerard Nash

Published: March 20, 2014
https://doi.org/10.1371/journal.pone.0091334

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Endothelial cells
Is the Subject Area "Endothelial cells" applicable to this article?

Thanks for your feedback.
Homeobox
Is the Subject Area "Homeobox" applicable to this article?

Thanks for your feedback.
Microarrays
Is the Subject Area "Microarrays" applicable to this article?

Thanks for your feedback.
Gene expression
Is the Subject Area "Gene expression" applicable to this article?

Thanks for your feedback.
Pulmonary arteries
Is the Subject Area "Pulmonary arteries" applicable to this article?

Thanks for your feedback.
Angiogenesis
Is the Subject Area "Angiogenesis" applicable to this article?

Thanks for your feedback.
Transcriptome analysis
Is the Subject Area "Transcriptome analysis" applicable to this article?

Thanks for your feedback.
Cell differentiation
Is the Subject Area "Cell differentiation" applicable to this article?

Thanks for your feedback.