Development of a Novel Severe Triple Allergen Asthma Model in Mice Which Is Resistant to Dexamethasone and Partially Resistant to TLR7 and TLR9 Agonist Treatment

Open Access

Peer-reviewed

Research Article

Matthias J. Duechs,

Affiliation Respiratory Diseases Research, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach a.d. Riss, Germany
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Cornelia Tilp,

Affiliation Respiratory Diseases Research, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach a.d. Riss, Germany
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Christopher Tomsic,

Affiliation Respiratory Diseases Research, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach a.d. Riss, Germany
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Florian Gantner,

Affiliation Respiratory Diseases Research, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach a.d. Riss, Germany
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Klaus J. Erb

* E-mail: klaus.erb@bc.boehringer-ingelheim.com

Affiliation Respiratory Diseases Research, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach a.d. Riss, Germany
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Allergens
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Asthma
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Mucus
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Mouse models
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Smooth muscles
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Collagens
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Inflammation
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Steroids
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