Two-Stage pH Control Strategy Based on the pH Preference of Acetoin Reductase Regulates Acetoin and 2,3-Butanediol Distribution in Bacillus subtilis

• Xian Zhang ,

  Contributed equally to this work with: Xian Zhang, Teng Bao

  Affiliation The Key Laboratory of Industrial Biotechnology of Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, Jiangsu, P. R. China

  ⨯
• Teng Bao ,

  Contributed equally to this work with: Xian Zhang, Teng Bao

  Affiliation The Key Laboratory of Industrial Biotechnology of Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, Jiangsu, P. R. China

  ⨯
• Zhiming Rao ,

  * E-mail: raozhm@jiangnan.edu.cn (ZR); hzhli@jiangnan.edu.cn (HL)

  Affiliation The Key Laboratory of Industrial Biotechnology of Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, Jiangsu, P. R. China

  ⨯
• Taowei Yang,

  Affiliation The Key Laboratory of Industrial Biotechnology of Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, Jiangsu, P. R. China

  ⨯
• Zhenghong Xu,

  Affiliation School of Medicine and Pharmaceuticals, Jiangnan University, Wuxi, Jiangsu, P. R. China

  ⨯
• Shangtian Yang,

  Affiliation Department of Chemical Engineering, Ohio State University, Columbus, Ohio, United States of America

  ⨯
• Huazhong Li

  * E-mail: raozhm@jiangnan.edu.cn (ZR); hzhli@jiangnan.edu.cn (HL)

  Affiliation The Key Laboratory of Industrial Biotechnology of Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, Jiangsu, P. R. China

  ⨯