Prion Protein-Specific Antibodies that Detect Multiple TSE Agents with High Sensitivity

Sandra McCutcheon; Jan P. M. Langeveld; Boon Chin Tan; Andrew C. Gill; Christopher de Wolf; Stuart Martin; Lorenzo Gonzalez; James Alibhai; A. Richard Alejo Blanco; Lauren Campbell; Nora Hunter; E. Fiona Houston

doi:10.1371/journal.pone.0091143

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Open Access

Peer-reviewed

Research Article

Prion Protein-Specific Antibodies that Detect Multiple TSE Agents with High Sensitivity

Sandra McCutcheon ,

* E-mail: sandra.mccutcheon@roslin.ed.ac.uk

Affiliation Neurobiology Division, The Roslin Institute and Royal (Dick) School of Veterinary Sciences, Easter Bush, Edinburgh, Scotland, United Kingdom
⨯
Jan P. M. Langeveld,

Affiliation Central Veterinary Institute of Wageningen UR, Lelystad, The Netherlands
⨯
Boon Chin Tan,

Affiliation Neurobiology Division, The Roslin Institute and Royal (Dick) School of Veterinary Sciences, Easter Bush, Edinburgh, Scotland, United Kingdom
⨯
Andrew C. Gill,

Affiliation Neurobiology Division, The Roslin Institute and Royal (Dick) School of Veterinary Sciences, Easter Bush, Edinburgh, Scotland, United Kingdom
⨯
Christopher de Wolf,

Affiliation Neurobiology Division, The Roslin Institute and Royal (Dick) School of Veterinary Sciences, Easter Bush, Edinburgh, Scotland, United Kingdom
⨯
Stuart Martin,

Affiliation Animal Health and Veterinary Laboratories Agency, Lasswade Laboratory, Edinburgh, Scotland, United Kingdom
⨯
Lorenzo Gonzalez,

Affiliation Animal Health and Veterinary Laboratories Agency, Lasswade Laboratory, Edinburgh, Scotland, United Kingdom
⨯
James Alibhai,

Affiliation Neurobiology Division, The Roslin Institute and Royal (Dick) School of Veterinary Sciences, Easter Bush, Edinburgh, Scotland, United Kingdom
⨯
A. Richard Alejo Blanco,

Affiliation Neurobiology Division, The Roslin Institute and Royal (Dick) School of Veterinary Sciences, Easter Bush, Edinburgh, Scotland, United Kingdom
⨯
Lauren Campbell,

Affiliation Neurobiology Division, The Roslin Institute and Royal (Dick) School of Veterinary Sciences, Easter Bush, Edinburgh, Scotland, United Kingdom
⨯
Nora Hunter,

Affiliation Neurobiology Division, The Roslin Institute and Royal (Dick) School of Veterinary Sciences, Easter Bush, Edinburgh, Scotland, United Kingdom
⨯
E. Fiona Houston

Affiliation Neurobiology Division, The Roslin Institute and Royal (Dick) School of Veterinary Sciences, Easter Bush, Edinburgh, Scotland, United Kingdom
⨯

Prion Protein-Specific Antibodies that Detect Multiple TSE Agents with High Sensitivity

Sandra McCutcheon,
Jan P. M. Langeveld,
Boon Chin Tan,
Andrew C. Gill,
Christopher de Wolf,
Stuart Martin,
Lorenzo Gonzalez,
James Alibhai,
A. Richard Alejo Blanco,
Lauren Campbell

Published: March 7, 2014
https://doi.org/10.1371/journal.pone.0091143

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Immunohistochemistry techniques
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Antibodies
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Enzyme-linked immunoassays
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Bovine spongiform encephalopathy
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Protein sequencing
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