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Open Access

Peer-reviewed

Research Article

Chaihuang-Yishen Granule Inhibits Diabetic Kidney Disease in Rats through Blocking TGF-β/Smad3 Signaling

Ting Ting Zhao,

Affiliation Department of Pharmacology, Institute of Clinical Medical Sciences, China-Japan Friendship Hospital, Beijing, China
⨯
Hao Jun Zhang,

Affiliation Department of Pharmacology, Institute of Clinical Medical Sciences, China-Japan Friendship Hospital, Beijing, China
⨯
Xiao Guang Lu,

Affiliation Department of Pharmacology, Institute of Clinical Medical Sciences, China-Japan Friendship Hospital, Beijing, China
⨯
Xiao Ru Huang,

Affiliation Department of Medicine and Therapeutics, and Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong SAR; and CUHK Shenzhen Research Institute, Shenzhen, China
⨯
Wei Ku Zhang,

Affiliation Department of Pharmacology, Institute of Clinical Medical Sciences, China-Japan Friendship Hospital, Beijing, China
⨯
Hua Wang,

Affiliation Department of Pharmacology, Institute of Clinical Medical Sciences, China-Japan Friendship Hospital, Beijing, China
⨯
Hui Yao Lan ,

* E-mail: hylan@cuhk.edu.hk (HYL); lp8675@163.com (PL)

Affiliation Department of Medicine and Therapeutics, and Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong SAR; and CUHK Shenzhen Research Institute, Shenzhen, China
⨯
Ping Li

* E-mail: hylan@cuhk.edu.hk (HYL); lp8675@163.com (PL)

Affiliation Department of Pharmacology, Institute of Clinical Medical Sciences, China-Japan Friendship Hospital, Beijing, China
⨯

Chaihuang-Yishen Granule Inhibits Diabetic Kidney Disease in Rats through Blocking TGF-β/Smad3 Signaling

Ting Ting Zhao,
Hao Jun Zhang,
Xiao Guang Lu,
Xiao Ru Huang,
Wei Ku Zhang,
Hua Wang,
Hui Yao Lan,
Ping Li

x

Published: March 19, 2014
https://doi.org/10.1371/journal.pone.0090807

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Diabetes mellitus
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Kidneys
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Fibrosis
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SMAD signaling
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Signal inhibition
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Collagens
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High performance liquid chromatography
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Blood sugar
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