Lycium barbarum Polysaccharide Prevents Focal Cerebral Ischemic Injury by Inhibiting Neuronal Apoptosis in Mice

Tengfei Wang; Yuxiang Li; Yongsheng Wang; Ru Zhou; Lin Ma; Yinju Hao; Shaoju Jin; Juan Du; Chengjun Zhao; Tao Sun; Jianqiang Yu

doi:10.1371/journal.pone.0090780

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Open Access

Peer-reviewed

Research Article

Lycium barbarum Polysaccharide Prevents Focal Cerebral Ischemic Injury by Inhibiting Neuronal Apoptosis in Mice

Tengfei Wang ,

Contributed equally to this work with: Tengfei Wang, Yuxiang Li

Affiliation Department of Pharmacology, Ningxia Medical University, Yinchuan, People's Republic of China
⨯
Yuxiang Li ,

Contributed equally to this work with: Tengfei Wang, Yuxiang Li

Affiliation College of Nursing, Ningxia Medical University, Yinchuan, People's Republic of China
⨯
Yongsheng Wang,

Affiliation Department of Pharmacology, Ningxia Medical University, Yinchuan, People's Republic of China
⨯
Ru Zhou,

Affiliation Department of Pharmacology, Ningxia Medical University, Yinchuan, People's Republic of China
⨯
Lin Ma,

Affiliation Key Lab of Craniocerebral Diseases of Ningxia Hui Autonomous Region, Ningxia Medical University, Yinchuan, People's Republic of China
⨯
Yinju Hao,

Affiliation Department of Pharmacology, Ningxia Medical University, Yinchuan, People's Republic of China
⨯
Shaoju Jin,

Affiliation Department of Pharmacology, Ningxia Medical University, Yinchuan, People's Republic of China
⨯
Juan Du,

Affiliation Department of Pharmacology, Ningxia Medical University, Yinchuan, People's Republic of China
⨯
Chengjun Zhao,

Affiliation Key Laboratory of Fertility Preservation and Maintenance, Ningxia Medical University, Yinchuan, People's Republic of China
⨯
Tao Sun,

Affiliation Key Lab of Craniocerebral Diseases of Ningxia Hui Autonomous Region, Ningxia Medical University, Yinchuan, People's Republic of China
⨯
Jianqiang Yu

* E-mail: yujq910315@163.com

Affiliations Department of Pharmacology, Ningxia Medical University, Yinchuan, People's Republic of China, Ningxia Hui Medicine Modern Engineering Research Center, Ningxia Medical University, Yinchuan, People's Republic of China
⨯

Lycium barbarum Polysaccharide Prevents Focal Cerebral Ischemic Injury by Inhibiting Neuronal Apoptosis in Mice

Tengfei Wang,
Yuxiang Li,
Yongsheng Wang,
Ru Zhou,
Lin Ma,
Yinju Hao,
Shaoju Jin,
Juan Du,
Chengjun Zhao,
Tao Sun

Published: March 3, 2014
https://doi.org/10.1371/journal.pone.0090780

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Apoptosis
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Cerebral ischemia
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Reperfusion
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Mitochondria
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Hematoxylin staining
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Protein expression
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Brain damage
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Neuronal tuning
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