Nucleolin Regulates Phosphorylation and Nuclear Export of Fibroblast Growth Factor 1 (FGF1)

Torunn Sletten; Michal Kostas; Joanna Bober; Vigdis Sorensen; Mandana Yadollahi; Sjur Olsnes; Justyna Tomala; Jacek Otlewski; Malgorzata Zakrzewska; Antoni Wiedlocha

doi:10.1371/journal.pone.0090687

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Open Access

Peer-reviewed

Research Article

Nucleolin Regulates Phosphorylation and Nuclear Export of Fibroblast Growth Factor 1 (FGF1)

Torunn Sletten,

Affiliations Department of Biochemistry, Institute for Cancer Research, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway, Centre for Cancer Biomedicine, Faculty of Medicine, University of Oslo, Norway
⨯
Michal Kostas,

Affiliation Department of Protein Biotechnology, Faculty of Biotechnology, University of Wroclaw, Wroclaw, Poland
⨯
Joanna Bober,

Affiliation Department of Protein Engineering, Faculty of Biotechnology, University of Wroclaw, Wroclaw, Poland
⨯
Vigdis Sorensen,

Affiliations Department of Biochemistry, Institute for Cancer Research, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway, Centre for Cancer Biomedicine, Faculty of Medicine, University of Oslo, Norway
⨯
Mandana Yadollahi,

Affiliations Department of Biochemistry, Institute for Cancer Research, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway, Centre for Cancer Biomedicine, Faculty of Medicine, University of Oslo, Norway
⨯
Sjur Olsnes,

Affiliations Department of Biochemistry, Institute for Cancer Research, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway, Centre for Cancer Biomedicine, Faculty of Medicine, University of Oslo, Norway
⨯
Justyna Tomala,

Affiliation Department of Protein Biotechnology, Faculty of Biotechnology, University of Wroclaw, Wroclaw, Poland
⨯
Jacek Otlewski,

Affiliation Department of Protein Engineering, Faculty of Biotechnology, University of Wroclaw, Wroclaw, Poland
⨯
Malgorzata Zakrzewska ,

* E-mail: antoni.wiedlocha@rr-research.no (AW); malgorzata.zakrzewska@uni.wroc.pl (MZ)

Affiliation Department of Protein Engineering, Faculty of Biotechnology, University of Wroclaw, Wroclaw, Poland
⨯
Antoni Wiedlocha

* E-mail: antoni.wiedlocha@rr-research.no (AW); malgorzata.zakrzewska@uni.wroc.pl (MZ)

Affiliations Department of Biochemistry, Institute for Cancer Research, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway, Centre for Cancer Biomedicine, Faculty of Medicine, University of Oslo, Norway
⨯

Nucleolin Regulates Phosphorylation and Nuclear Export of Fibroblast Growth Factor 1 (FGF1)

Torunn Sletten,
Michal Kostas,
Joanna Bober,
Vigdis Sorensen,
Mandana Yadollahi,
Sjur Olsnes,
Justyna Tomala,
Jacek Otlewski,
Malgorzata Zakrzewska,
Antoni Wiedlocha

Published: March 4, 2014
https://doi.org/10.1371/journal.pone.0090687

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Phosphorylation
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Fibroblast growth factor
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Small interfering RNA
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Cytosol
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Transfection
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Heparin
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Immunoblotting
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Nuclear import
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