Macrophage Contact Dependent and Independent TLR4 Mechanisms Induce β-Cell Dysfunction and Apoptosis in a Mouse Model of Type 2 Diabetes

Open Access

Peer-reviewed

Research Article

Helena Cucak,

Affiliation Hagedorn Research Institute, Department of Diabetic Complication Biology, Måløv, Denmark
⨯
Christopher Mayer,

Affiliation Hagedorn Research Institute, Department of Diabetic Complication Biology, Måløv, Denmark
⨯
Morten Tonnesen,

Affiliation Hagedorn Research Institute, Department of Diabetic Complication Biology, Måløv, Denmark
⨯
Lise Høj Thomsen,

Affiliation Hagedorn Research Institute, Department of Diabetic Complication Biology, Måløv, Denmark
⨯
Lars Groth Grunnet,

Affiliation Department of Incretin & Islet Biology, Måløv, Denmark
⨯
Alexander Rosendahl

* E-mail: AXRD@novonordisk.com

Affiliation Hagedorn Research Institute, Department of Diabetic Complication Biology, Måløv, Denmark
⨯

Reader Comments (0)

Macrophages
Is the Subject Area "Macrophages" applicable to this article?

Thanks for your feedback.
Diabetes mellitus
Is the Subject Area "Diabetes mellitus" applicable to this article?

Thanks for your feedback.
Cytokines
Is the Subject Area "Cytokines" applicable to this article?

Thanks for your feedback.
Apoptosis
Is the Subject Area "Apoptosis" applicable to this article?

Thanks for your feedback.
Toll-like receptors
Is the Subject Area "Toll-like receptors" applicable to this article?

Thanks for your feedback.
Mouse models
Is the Subject Area "Mouse models" applicable to this article?

Thanks for your feedback.
Glucose
Is the Subject Area "Glucose" applicable to this article?

Thanks for your feedback.
Insulin
Is the Subject Area "Insulin" applicable to this article?

Thanks for your feedback.