The Bitter Barricading of Prostaglandin Biosynthesis Pathway: Understanding the Molecular Mechanism of Selective Cyclooxygenase-2 Inhibition by Amarogentin, a Secoiridoid Glycoside from Swertia chirayita

• Shantanu Shukla ,

  Contributed equally to this work with: Shantanu Shukla, Khushboo Bafna

  Affiliation Bioresource Database and Bioinformatics Division, Regional Center of Institute of Bioresources and Sustainable Development, Tadong, Gangtok, Sikkim, India

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• Khushboo Bafna ,

  Contributed equally to this work with: Shantanu Shukla, Khushboo Bafna

  Affiliation Department of Biochemical Engineering and Biotechnology, Indian Institute of Technology Delhi, Hauz Khas, New Delhi, India

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• Durai Sundar ,

  * E-mail: sunilsthorat.ibsd@nic.in (SST); sundar@dbeb.iitd.ac.in (DS)

  Affiliation Department of Biochemical Engineering and Biotechnology, Indian Institute of Technology Delhi, Hauz Khas, New Delhi, India

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• Sunil S. Thorat

  * E-mail: sunilsthorat.ibsd@nic.in (SST); sundar@dbeb.iitd.ac.in (DS)

  Affiliations Bioresource Database and Bioinformatics Division, Regional Center of Institute of Bioresources and Sustainable Development, Tadong, Gangtok, Sikkim, India, Distributed Information Sub-Centre, Institute of Bioresources and Sustainable Development, Imphal, Manipur, India

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