Casein Kinase II Induced Polymerization of Soluble TDP-43 into Filaments Is Inhibited by Heat Shock Proteins

Open Access

Peer-reviewed

Research Article

Yari Carlomagno ,

Contributed equally to this work with: Yari Carlomagno, Yongjie Zhang

Affiliation Department of Neuroscience, Maya Clinic, Jacksonville, Florida, United States of America
⨯
Yongjie Zhang ,

Contributed equally to this work with: Yari Carlomagno, Yongjie Zhang

Affiliation Department of Neuroscience, Maya Clinic, Jacksonville, Florida, United States of America
⨯
Mary Davis,

Affiliation Department of Neuroscience, Maya Clinic, Jacksonville, Florida, United States of America
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Wen-Lang Lin,

Affiliation Department of Neuroscience, Maya Clinic, Jacksonville, Florida, United States of America
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Casey Cook,

Affiliation Department of Neuroscience, Maya Clinic, Jacksonville, Florida, United States of America
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Judy Dunmore,

Affiliation Department of Neuroscience, Maya Clinic, Jacksonville, Florida, United States of America
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William Tay,

Affiliation Department of Neuroscience, Maya Clinic, Jacksonville, Florida, United States of America
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Kyle Menkosky,

Affiliation Department of Neuroscience, Maya Clinic, Jacksonville, Florida, United States of America
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Xiangkun Cao,

Affiliation Department of Neuroscience, Maya Clinic, Jacksonville, Florida, United States of America
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Leonard Petrucelli,

Affiliation Department of Neuroscience, Maya Clinic, Jacksonville, Florida, United States of America
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Michael DeTure

* E-mail: deture.michael@mayo.edu

Affiliation Department of Neuroscience, Maya Clinic, Jacksonville, Florida, United States of America
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Phosphorylation
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Polymerization
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DNA-binding proteins
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Cytoplasmic inclusions
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Electron microscopy
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Heat shock response
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Nitrocellulose
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Amyotrophic lateral sclerosis
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