Monocytes Expand with Immune Dysregulation and Is Associated with Insulin Resistance in Older Individuals with Chronic HIV

Cecilia M. Shikuma; Dominic C. Chow; Louie Mar A. Gangcuangco; Guangxiang Zhang; Sheila M. Keating; Philip J. Norris; Todd B. Seto; Nisha Parikh; Kalpana J. Kallianpur; Beau K. Nakamoto; Lorna S. Nagamine; Lishomwa C. Ndhlovu; Jason D. Barbour

doi:10.1371/journal.pone.0090330

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Open Access

Peer-reviewed

Research Article

Monocytes Expand with Immune Dysregulation and Is Associated with Insulin Resistance in Older Individuals with Chronic HIV

Cecilia M. Shikuma ,

* E-mail: shikuma@hawaii.edu

Affiliation Hawaii Center for AIDS, University of Hawaii, Honolulu, Hawaii, United States of America
⨯
Dominic C. Chow,

Affiliation Hawaii Center for AIDS, University of Hawaii, Honolulu, Hawaii, United States of America
⨯
Louie Mar A. Gangcuangco,

Affiliation Hawaii Center for AIDS, University of Hawaii, Honolulu, Hawaii, United States of America
⨯
Guangxiang Zhang,

Affiliation Hawaii Center for AIDS, University of Hawaii, Honolulu, Hawaii, United States of America
⨯
Sheila M. Keating,

Affiliation Blood Systems Research Institute, San Francisco, California, United States of America
⨯
Philip J. Norris,

Affiliations Blood Systems Research Institute, San Francisco, California, United States of America, University of California San Francisco, San Francisco, California, United States of America
⨯
Todd B. Seto,

Affiliations Hawaii Center for AIDS, University of Hawaii, Honolulu, Hawaii, United States of America, Queen’s Medical Center, Honolulu, Hawaii, United States of America
⨯
Nisha Parikh,

Affiliations Hawaii Center for AIDS, University of Hawaii, Honolulu, Hawaii, United States of America, Queen’s Medical Center, Honolulu, Hawaii, United States of America
⨯
Kalpana J. Kallianpur,

Affiliation Hawaii Center for AIDS, University of Hawaii, Honolulu, Hawaii, United States of America
⨯
Beau K. Nakamoto,

Affiliations Hawaii Center for AIDS, University of Hawaii, Honolulu, Hawaii, United States of America, Straub Clinic and Hospital, Honolulu, Hawaii, United States of America
⨯
Lorna S. Nagamine,

Affiliation Hawaii Center for AIDS, University of Hawaii, Honolulu, Hawaii, United States of America
⨯
Lishomwa C. Ndhlovu,

Affiliation Hawaii Center for AIDS, University of Hawaii, Honolulu, Hawaii, United States of America
⨯
Jason D. Barbour

Affiliation Hawaii Center for AIDS, University of Hawaii, Honolulu, Hawaii, United States of America
⨯

Monocytes Expand with Immune Dysregulation and Is Associated with Insulin Resistance in Older Individuals with Chronic HIV

Cecilia M. Shikuma,
Dominic C. Chow,
Louie Mar A. Gangcuangco,
Guangxiang Zhang,
Sheila M. Keating,
Philip J. Norris,
Todd B. Seto,
Nisha Parikh,
Kalpana J. Kallianpur,
Beau K. Nakamoto

Published: February 27, 2014
https://doi.org/10.1371/journal.pone.0090330

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