Highly Efficient Expression of Interleukin-2 under the Control of Rabbit β-Globin Intron II Gene Enhances Protective Immune Responses of Porcine Reproductive and Respiratory Syndrome (PRRS) DNA Vaccine in Pigs

• Yijun Du ,

  Contributed equally to this work with: Yijun Du, Yu Lu, Xinglong Wang, Jing Qi

  Affiliations School of Life Sciences, Shandong University, Jinan, China, Shandong Key Laboratory of Animal Disease Control and Breeding, Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Jinan, China

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• Yu Lu ,

  Contributed equally to this work with: Yijun Du, Yu Lu, Xinglong Wang, Jing Qi

  Affiliation National Research Center of Veterinary Biologicals Engineering and Technology, Jiangsu Academy of Agricultural Sciences, Nanjing, China

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• Xinglong Wang ,

  Contributed equally to this work with: Yijun Du, Yu Lu, Xinglong Wang, Jing Qi

  Affiliation College of Veterinary Medicine, Northwest A&F University, Yangling, China

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• Jing Qi ,

  Contributed equally to this work with: Yijun Du, Yu Lu, Xinglong Wang, Jing Qi

  Affiliations School of Life Sciences, Shandong University, Jinan, China, Shandong Key Laboratory of Animal Disease Control and Breeding, Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Jinan, China

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• Jiyu Liu,

  Affiliation Shandong Key Laboratory of Animal Disease Control and Breeding, Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Jinan, China

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• Yue Hu,

  Affiliation College of Animal Science & Veterinary Medicine, Shandong Agricultural University, Tai'an, China

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• Feng Li,

  Affiliation Department of Biology and Microbiology, Department of Veterinary and Biomedical Sciences, South Dakota State University, Brookings, South Dakota, United States of America

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• Jiaqiang Wu,

  Affiliation Shandong Key Laboratory of Animal Disease Control and Breeding, Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Jinan, China

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• Lihui Guo,

  Affiliation Shandong Key Laboratory of Animal Disease Control and Breeding, Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Jinan, China

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• Junzhen Liu,

  Affiliation Shandong Key Laboratory of Animal Disease Control and Breeding, Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Jinan, China

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• Haiying Tao,

  Affiliation Shandong Key Laboratory of Animal Disease Control and Breeding, Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Jinan, China

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• Wenbo Sun,

  Affiliation Shandong Key Laboratory of Animal Disease Control and Breeding, Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Jinan, China

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• Lei Chen,

  Affiliations School of Life Sciences, Shandong University, Jinan, China, Shandong Key Laboratory of Animal Disease Control and Breeding, Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Jinan, China

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• Xiaoyan Cong,

  Affiliations School of Life Sciences, Shandong University, Jinan, China, Shandong Key Laboratory of Animal Disease Control and Breeding, Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Jinan, China

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• Sufang Ren,

  Affiliation Shandong Key Laboratory of Animal Disease Control and Breeding, Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Jinan, China

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• Jianli Shi,

  Affiliation Shandong Key Laboratory of Animal Disease Control and Breeding, Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Jinan, China

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• Jun Li,

  Affiliation Shandong Key Laboratory of Animal Disease Control and Breeding, Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Jinan, China

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• Jinbao Wang ,

  * E-mail: wangjb@saas.ac.cn (JW); jn-hbh@163.com (BH); wrzh63@163.com (RW)

  Affiliations School of Life Sciences, Shandong University, Jinan, China, Shandong Key Laboratory of Animal Disease Control and Breeding, Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Jinan, China, College of Animal Science & Veterinary Medicine, Shandong Agricultural University, Tai'an, China

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• Baohua Huang ,

  * E-mail: wangjb@saas.ac.cn (JW); jn-hbh@163.com (BH); wrzh63@163.com (RW)

  Affiliation Shandong Key Laboratory of Animal Disease Control and Breeding, Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Jinan, China

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•  [ ... ],
• Renzhong Wan

  * E-mail: wangjb@saas.ac.cn (JW); jn-hbh@163.com (BH); wrzh63@163.com (RW)

  Affiliation College of Animal Science & Veterinary Medicine, Shandong Agricultural University, Tai'an, China

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