A Compensatory Role of NF-κB to p53 in Response to 5-FU–Based Chemotherapy for Gastric Cancer Cell Lines

Fumitaka Endo; Satoshi S. Nishizuka; Kohei Kume; Kazushige Ishida; Hirokatsu Katagiri; Kaoru Ishida; Kei Sato; Takeshi Iwaya; Keisuke Koeda; Go Wakabayashi

doi:10.1371/journal.pone.0090155

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Open Access

Peer-reviewed

Research Article

A Compensatory Role of NF-κB to p53 in Response to 5-FU–Based Chemotherapy for Gastric Cancer Cell Lines

Fumitaka Endo,

Affiliations Molecular Therapeutics Laboratory, Iwate Medical University School of Medicine, Morioka, Japan, Department of Surgery, Iwate Medical University School of Medicine, Morioka, Japan
⨯
Satoshi S. Nishizuka ,

* E-mail: snishizu@iwate-med.ac.jp

Affiliations Molecular Therapeutics Laboratory, Iwate Medical University School of Medicine, Morioka, Japan, Department of Surgery, Iwate Medical University School of Medicine, Morioka, Japan, MIAST (Medical Innovation by Advanced Science and Technology) project, Iwate Medical University, Morioka, Japan, Institute for Biomedical Sciences, Iwate Medical University, Yahaba, Japan
⨯
Kohei Kume,

Affiliations Molecular Therapeutics Laboratory, Iwate Medical University School of Medicine, Morioka, Japan, Department of Surgery, Iwate Medical University School of Medicine, Morioka, Japan, MIAST (Medical Innovation by Advanced Science and Technology) project, Iwate Medical University, Morioka, Japan, Institute for Biomedical Sciences, Iwate Medical University, Yahaba, Japan
⨯
Kazushige Ishida,

Affiliations Molecular Therapeutics Laboratory, Iwate Medical University School of Medicine, Morioka, Japan, Department of Surgery, Iwate Medical University School of Medicine, Morioka, Japan
⨯
Hirokatsu Katagiri,

Affiliations Molecular Therapeutics Laboratory, Iwate Medical University School of Medicine, Morioka, Japan, Department of Surgery, Iwate Medical University School of Medicine, Morioka, Japan
⨯
Kaoru Ishida,

Affiliations Molecular Therapeutics Laboratory, Iwate Medical University School of Medicine, Morioka, Japan, Department of Surgery, Iwate Medical University School of Medicine, Morioka, Japan
⨯
Kei Sato,

Affiliations Molecular Therapeutics Laboratory, Iwate Medical University School of Medicine, Morioka, Japan, Department of Surgery, Iwate Medical University School of Medicine, Morioka, Japan
⨯
Takeshi Iwaya,

Affiliations Molecular Therapeutics Laboratory, Iwate Medical University School of Medicine, Morioka, Japan, Department of Surgery, Iwate Medical University School of Medicine, Morioka, Japan
⨯
Keisuke Koeda,

Affiliation Department of Surgery, Iwate Medical University School of Medicine, Morioka, Japan
⨯
Go Wakabayashi

Affiliation Department of Surgery, Iwate Medical University School of Medicine, Morioka, Japan
⨯

A Compensatory Role of NF-κB to p53 in Response to 5-FU–Based Chemotherapy for Gastric Cancer Cell Lines

Fumitaka Endo,
Satoshi S. Nishizuka,
Kohei Kume,
Kazushige Ishida,
Hirokatsu Katagiri,
Kaoru Ishida,
Kei Sato,
Takeshi Iwaya,
Keisuke Koeda,
Go Wakabayashi

Published: February 27, 2014
https://doi.org/10.1371/journal.pone.0090155

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