HIV-1 Adenoviral Vector Vaccines Expressing Multi-Trimeric BAFF and 4-1BBL Enhance T Cell Mediated Anti-Viral Immunity

Saravana Kanagavelu; James M. Termini; Sachin Gupta; Francesca N. Raffa; Katherine A. Fuller; Yaelis Rivas; Sakhi Philip; Richard S. Kornbluth; Geoffrey W. Stone

doi:10.1371/journal.pone.0090100

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Open Access

Peer-reviewed

Research Article

HIV-1 Adenoviral Vector Vaccines Expressing Multi-Trimeric BAFF and 4-1BBL Enhance T Cell Mediated Anti-Viral Immunity

Saravana Kanagavelu ,

Contributed equally to this work with: Saravana Kanagavelu, James M. Termini

Affiliation Department of Microbiology and Immunology, Miami Center for AIDS Research, and the Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, Florida, United States of America
⨯
James M. Termini ,

Contributed equally to this work with: Saravana Kanagavelu, James M. Termini

Affiliation Department of Microbiology and Immunology, Miami Center for AIDS Research, and the Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, Florida, United States of America
⨯
Sachin Gupta,

Affiliation Department of Microbiology and Immunology, Miami Center for AIDS Research, and the Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, Florida, United States of America
⨯
Francesca N. Raffa,

Affiliation Department of Microbiology and Immunology, Miami Center for AIDS Research, and the Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, Florida, United States of America
⨯
Katherine A. Fuller,

Affiliation Department of Microbiology and Immunology, Miami Center for AIDS Research, and the Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, Florida, United States of America
⨯
Yaelis Rivas,

Affiliation Department of Microbiology and Immunology, Miami Center for AIDS Research, and the Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, Florida, United States of America
⨯
Sakhi Philip,

Affiliation Department of Radiation Oncology, University of Miami Miller School of Medicine, Miami, Florida, United States of America
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Richard S. Kornbluth,

Affiliation Multimeric Biotherapeutics, Inc., La Jolla, California, United States of America
⨯
Geoffrey W. Stone

* E-mail: gstone@med.miami.edu

Affiliation Department of Microbiology and Immunology, Miami Center for AIDS Research, and the Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, Florida, United States of America
⨯

HIV-1 Adenoviral Vector Vaccines Expressing Multi-Trimeric BAFF and 4-1BBL Enhance T Cell Mediated Anti-Viral Immunity

Saravana Kanagavelu,
James M. Termini,
Sachin Gupta,
Francesca N. Raffa,
Katherine A. Fuller,
Yaelis Rivas,
Sakhi Philip,
Richard S. Kornbluth,
Geoffrey W. Stone

Published: February 28, 2014
https://doi.org/10.1371/journal.pone.0090100

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