Pretreatment of Epithelial Cells with Live Streptococcus pneumoniae Has No Detectable Effect on Influenza A Virus Replication In Vitro

Kang Ouyang; Shireen A. Woodiga; Varun Dwivedi; Carolyn M. Buckwalter; Anirudh K. Singh; Basavaraj Binjawadagi; Jagadish Hiremath; Cordelia Manickam; Rose Schleappi; Mahesh Khatri; Jianmin Wu; Samantha J. King; Gourapura J. Renukaradhya

doi:10.1371/journal.pone.0090066

Loading metrics

Open Access

Peer-reviewed

Research Article

Pretreatment of Epithelial Cells with Live Streptococcus pneumoniae Has No Detectable Effect on Influenza A Virus Replication In Vitro

Kang Ouyang,

Affiliations College of Animal Science and Technology, Guangxi University, Nanning, China, Food Animal Health Research Program (FAHRP), OARDC, Department of Veterinary Preventive Medicine, The Ohio State University, Wooster, Ohio, United States of America
⨯
Shireen A. Woodiga,

Affiliation Center for Microbial Pathogenesis, Nationwide Children's Hospital, Columbus, Ohio, United States of America
⨯
Varun Dwivedi,

Affiliation Food Animal Health Research Program (FAHRP), OARDC, Department of Veterinary Preventive Medicine, The Ohio State University, Wooster, Ohio, United States of America
⨯
Carolyn M. Buckwalter,

Affiliations Center for Microbial Pathogenesis, Nationwide Children's Hospital, Columbus, Ohio, United States of America, Department of Pediatrics, The Ohio State University, Columbus, Ohio, United States of America
⨯
Anirudh K. Singh,

Affiliation Center for Microbial Pathogenesis, Nationwide Children's Hospital, Columbus, Ohio, United States of America
⨯
Basavaraj Binjawadagi,

Affiliation Food Animal Health Research Program (FAHRP), OARDC, Department of Veterinary Preventive Medicine, The Ohio State University, Wooster, Ohio, United States of America
⨯
Jagadish Hiremath,

Affiliation Food Animal Health Research Program (FAHRP), OARDC, Department of Veterinary Preventive Medicine, The Ohio State University, Wooster, Ohio, United States of America
⨯
Cordelia Manickam,

Affiliation Food Animal Health Research Program (FAHRP), OARDC, Department of Veterinary Preventive Medicine, The Ohio State University, Wooster, Ohio, United States of America
⨯
Rose Schleappi,

Affiliation Food Animal Health Research Program (FAHRP), OARDC, Department of Veterinary Preventive Medicine, The Ohio State University, Wooster, Ohio, United States of America
⨯
Mahesh Khatri,

Affiliation Food Animal Health Research Program (FAHRP), OARDC, Department of Veterinary Preventive Medicine, The Ohio State University, Wooster, Ohio, United States of America
⨯
Jianmin Wu,

Affiliation College of Animal Science and Technology, Guangxi University, Nanning, China
⨯
Samantha J. King ,

* E-mail: gourapura.1@osu.edu (GJR); Samantha.King@nationwidechildrens.org (SJK)

Affiliations Center for Microbial Pathogenesis, Nationwide Children's Hospital, Columbus, Ohio, United States of America, Department of Pediatrics, The Ohio State University, Columbus, Ohio, United States of America
⨯
Gourapura J. Renukaradhya

* E-mail: gourapura.1@osu.edu (GJR); Samantha.King@nationwidechildrens.org (SJK)

Affiliation Food Animal Health Research Program (FAHRP), OARDC, Department of Veterinary Preventive Medicine, The Ohio State University, Wooster, Ohio, United States of America
⨯

Pretreatment of Epithelial Cells with Live Streptococcus pneumoniae Has No Detectable Effect on Influenza A Virus Replication In Vitro

Kang Ouyang,
Shireen A. Woodiga,
Varun Dwivedi,
Carolyn M. Buckwalter,
Anirudh K. Singh,
Basavaraj Binjawadagi,
Jagadish Hiremath,
Cordelia Manickam,
Rose Schleappi,
Mahesh Khatri

Published: March 3, 2014
https://doi.org/10.1371/journal.pone.0090066

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Influenza A virus
Is the Subject Area "Influenza A virus" applicable to this article?

Thanks for your feedback.
Pneumococcus
Is the Subject Area "Pneumococcus" applicable to this article?

Thanks for your feedback.
Epithelial cells
Is the Subject Area "Epithelial cells" applicable to this article?

Thanks for your feedback.
Viral replication
Is the Subject Area "Viral replication" applicable to this article?

Thanks for your feedback.
Swine
Is the Subject Area "Swine" applicable to this article?

Thanks for your feedback.
Bacterial pathogens
Is the Subject Area "Bacterial pathogens" applicable to this article?

Thanks for your feedback.
Human metapneumovirus infection
Is the Subject Area "Human metapneumovirus infection" applicable to this article?

Thanks for your feedback.
Influenza
Is the Subject Area "Influenza" applicable to this article?

Thanks for your feedback.