Malignant Pleural Effusion Supernatants Are Substitutes for Metastatic Pleural Tumor Tissues in EGFR Mutation Test in Patients with Advanced Lung Adenocarcinoma

Dan Liu; Yachao Lu; Zhenli Hu; Ning Wu; Xiaomeng Nie; Yang Xia; Yiping Han; Qiang Li; Guanshan Zhu; Chong Bai

doi:10.1371/journal.pone.0089946

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Open Access

Peer-reviewed

Research Article

Malignant Pleural Effusion Supernatants Are Substitutes for Metastatic Pleural Tumor Tissues in EGFR Mutation Test in Patients with Advanced Lung Adenocarcinoma

Dan Liu ,

Contributed equally to this work with: Dan Liu, Yachao Lu, Zhenli Hu

Affiliation Department of Respiratory Medicine, Changhai Hospital, The Second Military Medical University, Shanghai, China
⨯
Yachao Lu ,

Contributed equally to this work with: Dan Liu, Yachao Lu, Zhenli Hu

Affiliation Innovation Center China, AstraZeneca Global R&D, Shanghai, China
⨯
Zhenli Hu ,

Contributed equally to this work with: Dan Liu, Yachao Lu, Zhenli Hu

Affiliation Department of Respiratory Medicine, Changhai Hospital, The Second Military Medical University, Shanghai, China
⨯
Ning Wu,

Affiliation Department of Respiratory Medicine, Changhai Hospital, The Second Military Medical University, Shanghai, China
⨯
Xiaomeng Nie,

Affiliation Department of Respiratory Medicine, Changhai Hospital, The Second Military Medical University, Shanghai, China
⨯
Yang Xia,

Affiliation Department of Respiratory Medicine, Changhai Hospital, The Second Military Medical University, Shanghai, China
⨯
Yiping Han,

Affiliation Department of Respiratory Medicine, Changhai Hospital, The Second Military Medical University, Shanghai, China
⨯
Qiang Li,

Affiliation Department of Respiratory Medicine, Changhai Hospital, The Second Military Medical University, Shanghai, China
⨯
Guanshan Zhu,

Affiliation Innovation Center China, AstraZeneca Global R&D, Shanghai, China
⨯
Chong Bai

* E-mail: bc7878@sohu.com

Affiliation Department of Respiratory Medicine, Changhai Hospital, The Second Military Medical University, Shanghai, China
⨯

Malignant Pleural Effusion Supernatants Are Substitutes for Metastatic Pleural Tumor Tissues in EGFR Mutation Test in Patients with Advanced Lung Adenocarcinoma

Dan Liu,
Yachao Lu,
Zhenli Hu,
Ning Wu,
Xiaomeng Nie,
Yang Xia,
Yiping Han,
Qiang Li,
Guanshan Zhu,
Chong Bai

Published: February 28, 2014
https://doi.org/10.1371/journal.pone.0089946

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