Gpr48 Deficiency Induces Polycystic Kidney Lesions and Renal Fibrosis in Mice by Activating Wnt Signal Pathway

Open Access

Peer-reviewed

Research Article

Yongyan Dang,

Affiliation Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, China
⨯
Bei Liu,

Affiliation Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, China
⨯
Peng Xu,

Affiliation Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, China
⨯
Pingya Zhu,

Affiliation Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, China
⨯
Yimiao Zhai,

Affiliation Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, China
⨯
Mingyao Liu ,

* E-mail: mliu@lm.bio.ecnu.edu (ML); xyye@bio.ecnu.edu.cn (XY)

Affiliation Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, China
⨯
Xiyun Ye

* E-mail: mliu@lm.bio.ecnu.edu (ML); xyye@bio.ecnu.edu.cn (XY)

Affiliation Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, China
⨯

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Kidneys
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Mouse models
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Genetically modified animals
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Wnt signaling cascade
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Fibrosis
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Collagens
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Reverse transcriptase-polymerase chain reaction
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G protein coupled receptors
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