Randomized Pharmacokinetic Study Comparing Subcutaneous and Intravenous Palonosetron in Cancer Patients Treated with Platinum Based Chemotherapy

Belen Sadaba; Anabel del Barrio; Miguel Angel Campanero; Jose Ramon Azanza; Almudena Gomez-Guiu; Jose Maria Lopez-Picazo; Salvador Martin Algarra; Francisco Guillén Grimá; Maria Blanco Prieto; Jose Luis Perez-Gracia; Alfonso Gurpide

doi:10.1371/journal.pone.0089747

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Open Access

Peer-reviewed

Research Article

Randomized Pharmacokinetic Study Comparing Subcutaneous and Intravenous Palonosetron in Cancer Patients Treated with Platinum Based Chemotherapy

Belen Sadaba ,

* E-mail: bsadaba@unav.es

Affiliation Clinical Pharmacology Department, School of Pharmacy, Clinica Universidad Navarra, University of Navarra, Pamplona, Spain
⨯
Anabel del Barrio,

Affiliation Oncology Department, School of Pharmacy, Clinica Universidad Navarra, University of Navarra, Pamplona, Spain
⨯
Miguel Angel Campanero,

Affiliation Clinical Pharmacology Department, School of Pharmacy, Clinica Universidad Navarra, University of Navarra, Pamplona, Spain
⨯
Jose Ramon Azanza,

Affiliation Clinical Pharmacology Department, School of Pharmacy, Clinica Universidad Navarra, University of Navarra, Pamplona, Spain
⨯
Almudena Gomez-Guiu,

Affiliation Clinical Pharmacology Department, School of Pharmacy, Clinica Universidad Navarra, University of Navarra, Pamplona, Spain
⨯
Jose Maria Lopez-Picazo,

Affiliation Oncology Department, School of Pharmacy, Clinica Universidad Navarra, University of Navarra, Pamplona, Spain
⨯
Salvador Martin Algarra,

Affiliation Oncology Department, School of Pharmacy, Clinica Universidad Navarra, University of Navarra, Pamplona, Spain
⨯
Francisco Guillén Grimá,

Affiliation Department of Preventive Medicine, School of Pharmacy, Clinica Universidad Navarra, University of Navarra, Pamplona, Spain
⨯
Maria Blanco Prieto,

Affiliation Department of Pharmacy and Pharmaceutical Technology, School of Pharmacy, Clinica Universidad Navarra, University of Navarra, Pamplona, Spain
⨯
Jose Luis Perez-Gracia ,

Contributed equally to this work with: Jose Luis Perez-Gracia, Alfonso Gurpide

Affiliation Oncology Department, School of Pharmacy, Clinica Universidad Navarra, University of Navarra, Pamplona, Spain
⨯
Alfonso Gurpide

Contributed equally to this work with: Jose Luis Perez-Gracia, Alfonso Gurpide

Affiliation Oncology Department, School of Pharmacy, Clinica Universidad Navarra, University of Navarra, Pamplona, Spain
⨯

Randomized Pharmacokinetic Study Comparing Subcutaneous and Intravenous Palonosetron in Cancer Patients Treated with Platinum Based Chemotherapy

Belen Sadaba,
Anabel del Barrio,
Miguel Angel Campanero,
Jose Ramon Azanza,
Almudena Gomez-Guiu,
Jose Maria Lopez-Picazo,
Salvador Martin Algarra,
Francisco Guillén Grimá,
Maria Blanco Prieto,
Jose Luis Perez-Gracia

Published: February 27, 2014
https://doi.org/10.1371/journal.pone.0089747

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