Toll-Like Receptor Agonist Augments Virus-Like Particle-Mediated Protection from Ebola Virus with Transient Immune Activation

Karen A. O. Martins; Jesse T. Steffens; Sean A. van Tongeren; Jay B. Wells; Alison A. Bergeron; Samuel P. Dickson; John M. Dye; Andres M. Salazar; Sina Bavari

doi:10.1371/journal.pone.0089735

Loading metrics

Open Access

Peer-reviewed

Research Article

Toll-Like Receptor Agonist Augments Virus-Like Particle-Mediated Protection from Ebola Virus with Transient Immune Activation

Karen A. O. Martins,

Affiliation Molecular and Translational Sciences, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, United States of America
⨯
Jesse T. Steffens,

Affiliation Molecular and Translational Sciences, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, United States of America
⨯
Sean A. van Tongeren,

Affiliation Molecular and Translational Sciences, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, United States of America
⨯
Jay B. Wells,

Affiliation Molecular and Translational Sciences, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, United States of America
⨯
Alison A. Bergeron,

Affiliation Molecular and Translational Sciences, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, United States of America
⨯
Samuel P. Dickson,

Affiliation Office of Regulated Studies, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, United States of America
⨯
John M. Dye,

Affiliation Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, United States of America
⨯
Andres M. Salazar,

Affiliation Oncovir Inc., Washington, DC, United States of America
⨯
Sina Bavari

* E-mail: sina.bavari@us.army.mil

Affiliation Molecular and Translational Sciences, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, United States of America
⨯

Toll-Like Receptor Agonist Augments Virus-Like Particle-Mediated Protection from Ebola Virus with Transient Immune Activation

Karen A. O. Martins,
Jesse T. Steffens,
Sean A. van Tongeren,
Jay B. Wells,
Alison A. Bergeron,
Samuel P. Dickson,
John M. Dye,
Andres M. Salazar,
Sina Bavari

Published: February 24, 2014
https://doi.org/10.1371/journal.pone.0089735

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Vaccination and immunization
Is the Subject Area "Vaccination and immunization" applicable to this article?

Thanks for your feedback.
T cells
Is the Subject Area "T cells" applicable to this article?

Thanks for your feedback.
Viral vaccines
Is the Subject Area "Viral vaccines" applicable to this article?

Thanks for your feedback.
Cytokines
Is the Subject Area "Cytokines" applicable to this article?

Thanks for your feedback.
Immunologic adjuvants
Is the Subject Area "Immunologic adjuvants" applicable to this article?

Thanks for your feedback.
Antibodies
Is the Subject Area "Antibodies" applicable to this article?

Thanks for your feedback.
Chemokines
Is the Subject Area "Chemokines" applicable to this article?

Thanks for your feedback.
Ebola virus
Is the Subject Area "Ebola virus" applicable to this article?

Thanks for your feedback.