Combinatorial Assembly of Small Molecules into Bivalent Antagonists of TrkC or TrkA Receptors

Open Access

Peer-reviewed

Research Article

Fouad Brahimi ,

Contributed equally to this work with: Fouad Brahimi, Eunhwa Ko

Affiliation Lady Davis Institute-Jewish General Hospital, Montreal, Quebec, Canada
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Eunhwa Ko ,

Contributed equally to this work with: Fouad Brahimi, Eunhwa Ko

Affiliation Department of Chemistry, Texas A&M University. Texas, United States of America
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Andrey Malakhov,

Affiliation Department of Chemistry, Texas A&M University. Texas, United States of America
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Kevin Burgess,

Affiliation Department of Chemistry, Texas A&M University. Texas, United States of America
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H. Uri Saragovi

* E-mail: uri.saragovi@mcgill.ca

Affiliations Lady Davis Institute-Jewish General Hospital, Montreal, Quebec, Canada, Department of Pharmacology and Therapeutics, McGill University, Montreal, Quebec, Canada, Department of Oncology and the Cancer Center, McGill University, Montreal, Quebec, Canada
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Growth factors
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MAPK signaling cascades
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Apoptosis
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Binding analysis
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Biotin
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Cell binding assay
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MTT assay
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Tyrosine kinases
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