Arginine 199 and Leucine 208 Have Key Roles in the Control of Adenosine A2A Receptor Signalling Function

Open Access

Peer-reviewed

Research Article

Arginine 199 and Leucine 208 Have Key Roles in the Control of Adenosine A_2A Receptor Signalling Function

Nicolas Bertheleme,

Affiliation Department of Life Sciences, Imperial College London, London, United Kingdom
⨯
Annette Strege,

Affiliation Department of Life Sciences, Imperial College London, London, United Kingdom
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Sorrel E. Bunting,

Current address: King's College London, London, United Kingdom

Affiliation Department of Life Sciences, Imperial College London, London, United Kingdom
⨯
Simon J. Dowell,

Affiliation Department of Molecular Discovery Research, GlaxoSmithKline, Hertfordshire, United Kingdom
⨯
Bernadette Byrne

* E-mail: b.byrne@imperial.ac.uk

Affiliation Department of Life Sciences, Imperial College London, London, United Kingdom
⨯

Point mutation
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Yeast
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Substitution mutation
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Saccharomyces cerevisiae
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Adenosine
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Crystal structure
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Built structures
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Mutagenesis
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