Apolipoprotein E Plays a Key Role against Cryptosporidial Infection in Transgenic Undernourished Mice

Orleâncio G. R. Azevedo; David T. Bolick; James K. Roche; Relana F. Pinkerton; Aldo A. M. Lima; Michael P. Vitek; Cirle A. Warren; Reinaldo B. Oriá; Richard L. Guerrant

doi:10.1371/journal.pone.0089562

Loading metrics

Open Access

Peer-reviewed

Research Article

Apolipoprotein E Plays a Key Role against Cryptosporidial Infection in Transgenic Undernourished Mice

Orleâncio G. R. Azevedo,

Affiliations Division of Infectious Diseases and International Medicine, Center for Global Health, School of Medicine, University of Virginia, Charlottesville, Virginia, United States of America, Laboratory of the Biology of Tissue Healing, Ontogeny and Nutrition, Institute of the Brazilian Semi-arid, School of Medicine, Federal University of Ceara, Fortaleza, Ceará, Brazil
⨯
David T. Bolick,

Affiliation Division of Infectious Diseases and International Medicine, Center for Global Health, School of Medicine, University of Virginia, Charlottesville, Virginia, United States of America
⨯
James K. Roche,

Affiliation Division of Infectious Diseases and International Medicine, Center for Global Health, School of Medicine, University of Virginia, Charlottesville, Virginia, United States of America
⨯
Relana F. Pinkerton,

Affiliation Division of Infectious Diseases and International Medicine, Center for Global Health, School of Medicine, University of Virginia, Charlottesville, Virginia, United States of America
⨯
Aldo A. M. Lima,

Affiliations Division of Infectious Diseases and International Medicine, Center for Global Health, School of Medicine, University of Virginia, Charlottesville, Virginia, United States of America, Laboratory of Infectious Diseases, Clinical Research Unit, Institute of the Brazilian Semi-Arid, School of Medicine, Federal University of Ceara, Fortaleza, Ceará, Brazil
⨯
Michael P. Vitek,

Affiliation Duke University Medical Center, Department of Medicine, Durham, North Carolina, United States of America
⨯
Cirle A. Warren,

Affiliation Division of Infectious Diseases and International Medicine, Center for Global Health, School of Medicine, University of Virginia, Charlottesville, Virginia, United States of America
⨯
Reinaldo B. Oriá ,

* E-mail: oria@ufc.br

Affiliations Division of Infectious Diseases and International Medicine, Center for Global Health, School of Medicine, University of Virginia, Charlottesville, Virginia, United States of America, Laboratory of the Biology of Tissue Healing, Ontogeny and Nutrition, Institute of the Brazilian Semi-arid, School of Medicine, Federal University of Ceara, Fortaleza, Ceará, Brazil
⨯
Richard L. Guerrant

Affiliations Division of Infectious Diseases and International Medicine, Center for Global Health, School of Medicine, University of Virginia, Charlottesville, Virginia, United States of America, Laboratory of Infectious Diseases, Clinical Research Unit, Institute of the Brazilian Semi-Arid, School of Medicine, Federal University of Ceara, Fortaleza, Ceará, Brazil
⨯

Apolipoprotein E Plays a Key Role against Cryptosporidial Infection in Transgenic Undernourished Mice

Orleâncio G. R. Azevedo,
David T. Bolick,
James K. Roche,
Relana F. Pinkerton,
Aldo A. M. Lima,
Michael P. Vitek,
Cirle A. Warren,
Reinaldo B. Oriá,
Richard L. Guerrant

Published: February 28, 2014
https://doi.org/10.1371/journal.pone.0089562

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Mouse models
Is the Subject Area "Mouse models" applicable to this article?

Thanks for your feedback.
Genetically modified animals
Is the Subject Area "Genetically modified animals" applicable to this article?

Thanks for your feedback.
Cryptosporidium parvum
Is the Subject Area "Cryptosporidium parvum" applicable to this article?

Thanks for your feedback.
Oocysts
Is the Subject Area "Oocysts" applicable to this article?

Thanks for your feedback.
Malnutrition
Is the Subject Area "Malnutrition" applicable to this article?

Thanks for your feedback.
Gastrointestinal tract
Is the Subject Area "Gastrointestinal tract" applicable to this article?

Thanks for your feedback.
Cytokines
Is the Subject Area "Cytokines" applicable to this article?

Thanks for your feedback.
Animal models of infection
Is the Subject Area "Animal models of infection" applicable to this article?

Thanks for your feedback.