Ultrasound Can Detect Macroscopically Undetectable Changes in Osteoarthritis Reflecting the Superficial Histological and Biochemical Degeneration: Ex Vivo Study of Rabbit and Human Cartilage

• Kohei Nishitani ,

  * E-mail: nkohei@kuhp.kyoto-u.ac.jp

  Affiliation Department of Orthopaedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan

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• Masahiko Kobayashi,

  Affiliation Department of Orthopaedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan

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• Hiroshi Kuroki,

  Affiliation Department of Physical Therapy, Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan

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• Koji Mori,

  Affiliation Department of Applied Medical Engineering Science, Graduate School of Medicine, Yamaguchi University, Ube, Japan

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• Takaaki Shirai,

  Affiliation Department of Orthopaedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan

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• Tsuyoshi Satake,

  Affiliation Department of Orthopaedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan

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• Shinnichiro Nakamura,

  Affiliation Department of Orthopaedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan

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• Ryuzo Arai,

  Affiliation Department of Orthopaedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan

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• Yasuaki Nakagawa,

  Affiliations Department of Orthopaedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan, Department of Orthopaedic surgery, National Hospital Organization Kyoto Medical Center, Kyoto, Japan

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• Takashi Nakamura,

  Affiliations Department of Orthopaedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan, Department of Orthopaedic surgery, National Hospital Organization Kyoto Medical Center, Kyoto, Japan

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• Shuichi Matsuda

  Affiliation Department of Orthopaedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan

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