Disulfide Linkages in Plasmodium falciparum Plasmepsin-I Are Essential Elements for Its Processing Activity and Multi-Milligram Recombinant Production Yield

Open Access

Peer-reviewed

Research Article

Sirisak Lolupiman,

Affiliation Department of Biochemistry and Center for Excellence in Protein Structure and Function, Faculty of Science, Mahidol University, Bangkok, Thailand
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Pilaiwan Siripurkpong,

Affiliation Department of Medical Technology, Faculty of Allied Health Sciences, Thammasat University, Pathumthani, Thailand
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Jirundon Yuvaniyama

* E-mail: jirundon.yuv@mahidol.ac.th

Affiliation Department of Biochemistry and Center for Excellence in Protein Structure and Function, Faculty of Science, Mahidol University, Bangkok, Thailand
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Thiols
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Disulfide bonds
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Urea
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Zymogens
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Centrifugation
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Enzyme structure
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Malarial parasites
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Drug discovery
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