Premature CD4+ T Cell Aging and Its Contribution to Lymphopenia-Induced Proliferation of Memory Cells in Autoimmune-Prone Non-Obese Diabetic Mice

Open Access

Peer-reviewed

Research Article

Premature CD4⁺ T Cell Aging and Its Contribution to Lymphopenia-Induced Proliferation of Memory Cells in Autoimmune-Prone Non-Obese Diabetic Mice

Ting-Ting Sheu ,

* E-mail: tsheu1@mail.tcu.edu.tw

Affiliations Department of Immunology, Tzu Chi University, Hualien, Taiwan, Republic of China, Institute of Microbiology, Immunology and Biochemistry, Tzu Chi University, Hualien, Taiwan, Republic of China
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Bor-Luen Chiang,

Affiliations Graduate Institute of Immunology, National Taiwan University, Taipei, Taiwan, Republic of China, Department of Medical Research, National Taiwan University Hospital, Taipei, Taiwan, Republic of China
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Jui-Hung Yen,

Affiliation Department of Molecular Biology and Human Genetics, Tzu Chi University, Hualien, Taiwan, Republic of China
⨯
Wen-Chi Lin

Affiliation Institute of Microbiology, Immunology and Biochemistry, Tzu Chi University, Hualien, Taiwan, Republic of China
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T cells
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Cell aging
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Age groups
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Mouse models
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Aging
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Spleen
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Lymphopenia
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Autoimmune diseases
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