Genetic Association Analysis of ATP Binding Cassette Protein Family Reveals a Novel Association of ABCB1 Genetic Variants with Epilepsy Risk, but Not with Drug-Resistance

Shabeesh Balan; Sumitha Prameela Bharathan; Neetha Nanoth Vellichiramal; Sanish Sathyan; Vijai Joseph; Kurupath Radhakrishnan; Moinak Banerjee

doi:10.1371/journal.pone.0089253

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Peer-reviewed

Research Article

Genetic Association Analysis of ATP Binding Cassette Protein Family Reveals a Novel Association of ABCB1 Genetic Variants with Epilepsy Risk, but Not with Drug-Resistance

Shabeesh Balan,

Current address: Laboratory for Molecular Psychiatry, RIKEN Brain Science Institute, Saitama, Japan

Affiliations Human Molecular Genetics Laboratory, Rajiv Gandhi Center for Biotechnology, Trivandrum, Kerala, India, R. Madhavan Nayar Center for Comprehensive Epilepsy Care, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, Kerala, India
⨯
Sumitha Prameela Bharathan,

Current address: Centre for Stem Cell Research, Christian Medical College Campus, Vellore, India

Affiliation Human Molecular Genetics Laboratory, Rajiv Gandhi Center for Biotechnology, Trivandrum, Kerala, India
⨯
Neetha Nanoth Vellichiramal,

Current address: School of Biological Sciences, University of Nebraska Lincoln, Lincoln, Nebraska, United States of America

Affiliation Human Molecular Genetics Laboratory, Rajiv Gandhi Center for Biotechnology, Trivandrum, Kerala, India
⨯
Sanish Sathyan,

Affiliation Human Molecular Genetics Laboratory, Rajiv Gandhi Center for Biotechnology, Trivandrum, Kerala, India
⨯
Vijai Joseph,

Affiliation Department of Medicine, Memorial-Sloan Kettering Cancer Center, New York, New York, United States of America
⨯
Kurupath Radhakrishnan,

Current address: Department of Neurology, Kasturba Medical College (KMC), Manipal University, Manipal Karnataka, India

Affiliation R. Madhavan Nayar Center for Comprehensive Epilepsy Care, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, Kerala, India
⨯
Moinak Banerjee

* E-mail: mbanerjee@rgcb.res.in

Affiliation Human Molecular Genetics Laboratory, Rajiv Gandhi Center for Biotechnology, Trivandrum, Kerala, India
⨯

Genetic Association Analysis of ATP Binding Cassette Protein Family Reveals a Novel Association of ABCB1 Genetic Variants with Epilepsy Risk, but Not with Drug-Resistance

Shabeesh Balan,
Sumitha Prameela Bharathan,
Neetha Nanoth Vellichiramal,
Sanish Sathyan,
Vijai Joseph,
Kurupath Radhakrishnan,
Moinak Banerjee

Published: February 21, 2014
https://doi.org/10.1371/journal.pone.0089253

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