Defining the Interactions and Role of DCAF1/VPRBP in the DDB1-Cullin4A E3 Ubiquitin Ligase Complex Engaged by HIV-1 Vpr to Induce a G2 Cell Cycle Arrest

Open Access

Peer-reviewed

Research Article

Defining the Interactions and Role of DCAF1/VPRBP in the DDB1-Cullin4A E3 Ubiquitin Ligase Complex Engaged by HIV-1 Vpr to Induce a G₂ Cell Cycle Arrest

Francine C. A. Gérard,

Affiliation Institut de Recherches Cliniques de Montréal (IRCM), Montréal, Québec, Canada
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Ruifeng Yang,

Affiliation Institut de Recherches Cliniques de Montréal (IRCM), Montréal, Québec, Canada
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Bizhan Romani,

Affiliation Institut de Recherches Cliniques de Montréal (IRCM), Montréal, Québec, Canada
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Alexis Poisson,

Affiliation Institut de Recherches Cliniques de Montréal (IRCM), Montréal, Québec, Canada
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Jean-Philippe Belzile,

Affiliation Institut de Recherches Cliniques de Montréal (IRCM), Montréal, Québec, Canada
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Nicole Rougeau,

Affiliation Institut de Recherches Cliniques de Montréal (IRCM), Montréal, Québec, Canada
⨯
Éric A. Cohen

* E-mail: eric.cohen@ircm.qc.ca

Affiliations Institut de Recherches Cliniques de Montréal (IRCM), Montréal, Québec, Canada, Department of Microbiology, Infectiology and Immunology, Université de Montréal, Montréal, Québec, Canada
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Immunoprecipitation
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Ligases
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Small interfering RNA
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Transfection
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Cell cycle and cell division
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Protein structure prediction
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Plasmid construction
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Ubiquitin ligases
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