Proline-Hydroxylated Hypoxia-Inducible Factor 1α (HIF-1α) Upregulation in Human Tumours

Cameron E. Snell; Helen Turley; Alan McIntyre; Demin Li; Massimo Masiero; Christopher J. Schofield; Kevin C. Gatter; Adrian L. Harris; Francesco Pezzella

doi:10.1371/journal.pone.0088955

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Open Access

Peer-reviewed

Research Article

Proline-Hydroxylated Hypoxia-Inducible Factor 1α (HIF-1α) Upregulation in Human Tumours

Cameron E. Snell ,

* E-mail: Cameron.snell@gmail.com

Affiliation Tumour Pathology Group, Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom
⨯
Helen Turley,

Affiliation Tumour Pathology Group, Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom
⨯
Alan McIntyre,

Affiliation Molecular Oncology Laboratories, Department of Medical Oncology, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom
⨯
Demin Li,

Affiliation Haemato-Oncology Group, Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom
⨯
Massimo Masiero,

Affiliation Haemato-Oncology Group, Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom
⨯
Christopher J. Schofield,

Affiliation Chemistry Research Laboratory, University of Oxford, Oxford, United Kingdom
⨯
Kevin C. Gatter,

Affiliation Tumour Pathology Group, Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom
⨯
Adrian L. Harris,

Affiliation Molecular Oncology Laboratories, Department of Medical Oncology, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom
⨯
Francesco Pezzella

Affiliation Tumour Pathology Group, Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom
⨯

Proline-Hydroxylated Hypoxia-Inducible Factor 1α (HIF-1α) Upregulation in Human Tumours

Cameron E. Snell,
Helen Turley,
Alan McIntyre,
Demin Li,
Massimo Masiero,
Christopher J. Schofield,
Kevin C. Gatter,
Adrian L. Harris,
Francesco Pezzella

Published: February 12, 2014
https://doi.org/10.1371/journal.pone.0088955

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Hydroxylation
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Immunohistochemistry techniques
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Lung and intrathoracic tumors
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