Long-Term Activation upon Brief Exposure to Xanomleline Is Unique to M1 and M4 Subtypes of Muscarinic Acetylcholine Receptors

Open Access

Peer-reviewed

Research Article

Long-Term Activation upon Brief Exposure to Xanomleline Is Unique to M₁ and M₄ Subtypes of Muscarinic Acetylcholine Receptors

Eva Šantrůčková,

Affiliation Department of Experimental and Clinical Pharmacology, University of Minnesota College of Pharmacy, Minneapolis, United States of America
⨯
Vladimír Doležal,

Affiliation Institute of Physiology Academy of Sciences of the Czech Republic, Prague, Czech Republic
⨯
Esam E. El-Fakahany,

Affiliation Department of Experimental and Clinical Pharmacology, University of Minnesota College of Pharmacy, Minneapolis, United States of America
⨯
Jan Jakubík

* E-mail: jakubik@biomed.cas.cz

Affiliation Institute of Physiology Academy of Sciences of the Czech Republic, Prague, Czech Republic
⨯

Intracellular receptors
Is the Subject Area "Intracellular receptors" applicable to this article?

Thanks for your feedback.
Carbachol
Is the Subject Area "Carbachol" applicable to this article?

Thanks for your feedback.
Calcium signaling
Is the Subject Area "Calcium signaling" applicable to this article?

Thanks for your feedback.
Muscarinic acetylcholine receptors
Is the Subject Area "Muscarinic acetylcholine receptors" applicable to this article?

Thanks for your feedback.
Membrane receptor signaling
Is the Subject Area "Membrane receptor signaling" applicable to this article?

Thanks for your feedback.
CHO cells
Is the Subject Area "CHO cells" applicable to this article?

Thanks for your feedback.
Cell binding
Is the Subject Area "Cell binding" applicable to this article?

Thanks for your feedback.
G-protein signaling
Is the Subject Area "G-protein signaling" applicable to this article?

Thanks for your feedback.