Identification and Characterization of Sebaceous Gland Atrophy-Sparing DGAT1 Inhibitors

Eric S. Muise; Yonghua Zhu; Andreas Verras; Bindhu V. Karanam; Judith Gorski; Drew Weingarth; Hua V. Lin; Joyce Hwa; John R. Thompson; Guanghui Hu; Jian Liu; Shuwen He; Robert J. DeVita; Dong-Ming Shen; Shirly Pinto

doi:10.1371/journal.pone.0088908

Loading metrics

Open Access

Peer-reviewed

Research Article

Identification and Characterization of Sebaceous Gland Atrophy-Sparing DGAT1 Inhibitors

Eric S. Muise,

Affiliation Discovery and Preclinical Sciences, Merck Research Laboratories, Whithouse Station, New Jersey, United States of America
⨯
Yonghua Zhu,

Affiliation Discovery and Preclinical Sciences, Merck Research Laboratories, Whithouse Station, New Jersey, United States of America
⨯
Andreas Verras,

Affiliation Discovery and Preclinical Sciences, Merck Research Laboratories, Whithouse Station, New Jersey, United States of America
⨯
Bindhu V. Karanam,

Affiliation Discovery and Preclinical Sciences, Merck Research Laboratories, Whithouse Station, New Jersey, United States of America
⨯
Judith Gorski,

Affiliation Discovery and Preclinical Sciences, Merck Research Laboratories, Whithouse Station, New Jersey, United States of America
⨯
Drew Weingarth,

Affiliation Discovery and Preclinical Sciences, Merck Research Laboratories, Whithouse Station, New Jersey, United States of America
⨯
Hua V. Lin,

Affiliation Discovery and Preclinical Sciences, Merck Research Laboratories, Whithouse Station, New Jersey, United States of America
⨯
Joyce Hwa,

Affiliation Discovery and Preclinical Sciences, Merck Research Laboratories, Whithouse Station, New Jersey, United States of America
⨯
John R. Thompson,

Affiliation Discovery and Preclinical Sciences, Merck Research Laboratories, Whithouse Station, New Jersey, United States of America
⨯
Guanghui Hu,

Affiliation Discovery and Preclinical Sciences, Merck Research Laboratories, Whithouse Station, New Jersey, United States of America
⨯
Jian Liu,

Affiliation Discovery and Preclinical Sciences, Merck Research Laboratories, Whithouse Station, New Jersey, United States of America
⨯
Shuwen He,

Affiliation Discovery and Preclinical Sciences, Merck Research Laboratories, Whithouse Station, New Jersey, United States of America
⨯
Robert J. DeVita,

Affiliation Discovery and Preclinical Sciences, Merck Research Laboratories, Whithouse Station, New Jersey, United States of America
⨯
Dong-Ming Shen,

Affiliation Discovery and Preclinical Sciences, Merck Research Laboratories, Whithouse Station, New Jersey, United States of America
⨯
Shirly Pinto

* E-mail: shirly_pinto@merck.com

Affiliation Discovery and Preclinical Sciences, Merck Research Laboratories, Whithouse Station, New Jersey, United States of America
⨯

Identification and Characterization of Sebaceous Gland Atrophy-Sparing DGAT1 Inhibitors

Eric S. Muise,
Yonghua Zhu,
Andreas Verras,
Bindhu V. Karanam,
Judith Gorski,
Drew Weingarth,
Hua V. Lin,
Joyce Hwa,
John R. Thompson,
Guanghui Hu

Published: February 18, 2014
https://doi.org/10.1371/journal.pone.0088908

Reader Comments (1)

Post a new comment on this article

0 Responses

24 Apr 2014
17:15 GMT
Most Recent

Minor modification to Table 1. Posted by muise_eric on 24 Apr 2014 at 17:15 GMT

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Sebaceous glands
Is the Subject Area "Sebaceous glands" applicable to this article?

Thanks for your feedback.
Atrophy
Is the Subject Area "Atrophy" applicable to this article?

Thanks for your feedback.
Biomarkers
Is the Subject Area "Biomarkers" applicable to this article?

Thanks for your feedback.
Histology
Is the Subject Area "Histology" applicable to this article?

Thanks for your feedback.
Computer software
Is the Subject Area "Computer software" applicable to this article?

Thanks for your feedback.
Biopsy
Is the Subject Area "Biopsy" applicable to this article?

Thanks for your feedback.
Diet
Is the Subject Area "Diet" applicable to this article?

Thanks for your feedback.
Small molecules
Is the Subject Area "Small molecules" applicable to this article?

Thanks for your feedback.