Impaired Circulating CD4+LAP+ Regulatory T Cells in Patients with Acute Coronary Syndrome and Its Mechanistic Study

Zheng-Feng Zhu; Kai Meng; Yu-Cheng Zhong; Liang Qi; Xiao-Bo Mao; Kun-Wu Yu; Wei Zhang; Peng-Fei Zhu; Ze-Peng Ren; Bang-Wei Wu; Qin-Wei Ji; Xiang Wang; Qiu-Tang Zeng

doi:10.1371/journal.pone.0088775

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Open Access

Peer-reviewed

Research Article

Impaired Circulating CD4⁺LAP⁺ Regulatory T Cells in Patients with Acute Coronary Syndrome and Its Mechanistic Study

Zheng-Feng Zhu ,

Contributed equally to this work with: Zheng-Feng Zhu, Kai Meng, Yu-Cheng Zhong, Liang Qi

Affiliation Laboratory of Cardiovascular Immunology, Key Laboratory of Biological Targeted Therapy of the Ministry of Education, Institute of Cardiology, Union Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China
⨯
Kai Meng ,

Contributed equally to this work with: Zheng-Feng Zhu, Kai Meng, Yu-Cheng Zhong, Liang Qi

Affiliation Laboratory of Cardiovascular Immunology, Key Laboratory of Biological Targeted Therapy of the Ministry of Education, Institute of Cardiology, Union Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China
⨯
Yu-Cheng Zhong ,

Contributed equally to this work with: Zheng-Feng Zhu, Kai Meng, Yu-Cheng Zhong, Liang Qi

Affiliation Laboratory of Cardiovascular Immunology, Key Laboratory of Biological Targeted Therapy of the Ministry of Education, Institute of Cardiology, Union Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China
⨯
Liang Qi ,

Contributed equally to this work with: Zheng-Feng Zhu, Kai Meng, Yu-Cheng Zhong, Liang Qi

Affiliation Department of Radiology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China
⨯
Xiao-Bo Mao,

Affiliation Laboratory of Cardiovascular Immunology, Key Laboratory of Biological Targeted Therapy of the Ministry of Education, Institute of Cardiology, Union Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China
⨯
Kun-Wu Yu,

Affiliation Laboratory of Cardiovascular Immunology, Key Laboratory of Biological Targeted Therapy of the Ministry of Education, Institute of Cardiology, Union Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China
⨯
Wei Zhang,

Affiliation Laboratory of Cardiovascular Immunology, Key Laboratory of Biological Targeted Therapy of the Ministry of Education, Institute of Cardiology, Union Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China
⨯
Peng-Fei Zhu,

Affiliation Laboratory of Cardiovascular Immunology, Key Laboratory of Biological Targeted Therapy of the Ministry of Education, Institute of Cardiology, Union Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China
⨯
Ze-Peng Ren,

Affiliation Laboratory of Cardiovascular Immunology, Key Laboratory of Biological Targeted Therapy of the Ministry of Education, Institute of Cardiology, Union Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China
⨯
Bang-Wei Wu,

Affiliation Laboratory of Cardiovascular Immunology, Key Laboratory of Biological Targeted Therapy of the Ministry of Education, Institute of Cardiology, Union Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China
⨯
Qin-Wei Ji,

Affiliation Department of Cardiology, the People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China
⨯
Xiang Wang ,

* E-mail: zengqiutang@gmail.com (QTZ); wxiang128@yahoo.com.cn (XW)

Affiliation Laboratory of Cardiovascular Immunology, Key Laboratory of Biological Targeted Therapy of the Ministry of Education, Institute of Cardiology, Union Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China
⨯
Qiu-Tang Zeng

* E-mail: zengqiutang@gmail.com (QTZ); wxiang128@yahoo.com.cn (XW)

Affiliation Laboratory of Cardiovascular Immunology, Key Laboratory of Biological Targeted Therapy of the Ministry of Education, Institute of Cardiology, Union Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China
⨯

Impaired Circulating CD4⁺LAP⁺ Regulatory T Cells in Patients with Acute Coronary Syndrome and Its Mechanistic Study

Zheng-Feng Zhu,
Kai Meng,
Yu-Cheng Zhong,
Liang Qi,
Xiao-Bo Mao,
Kun-Wu Yu,
Wei Zhang,
Peng-Fei Zhu,
Ze-Peng Ren,
Bang-Wei Wu

Published: February 18, 2014
https://doi.org/10.1371/journal.pone.0088775

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