Preclinical Evidence of Rapid-Onset Antidepressant-Like Effect in Radix Polygalae Extract

Im-Joon Shin; Sung Un Son; Hyunwoo Park; Yoorim Kim; Sung Hyun Park; Kelley Swanberg; Joo-Yeon Shin; Sang-Kyu Ha; Yoonju Cho; Soo-Yong Bang; Jae-Hwan Lew; Seung-Hun Cho; Sungho Maeng

doi:10.1371/journal.pone.0088617

Loading metrics

Open Access

Peer-reviewed

Research Article

Preclinical Evidence of Rapid-Onset Antidepressant-Like Effect in Radix Polygalae Extract

Im-Joon Shin ,

Contributed equally to this work with: Im-Joon Shin, Sung Un Son

Affiliation Department of Applied Korean Medicine, College of Oriental Medicine, Kyung Hee University, Seoul, Korea
⨯
Sung Un Son ,

Contributed equally to this work with: Im-Joon Shin, Sung Un Son

Affiliation Department of East-West Medicine, Graduate School of East-West Medical Science, Kyung Hee University, Yongin, Korea
⨯
Hyunwoo Park,

Affiliation Department of East-West Medicine, Graduate School of East-West Medical Science, Kyung Hee University, Yongin, Korea
⨯
Yoorim Kim,

Affiliation Department of East-West Medicine, Graduate School of East-West Medical Science, Kyung Hee University, Yongin, Korea
⨯
Sung Hyun Park,

Affiliation Department of East-West Medicine, Graduate School of East-West Medical Science, Kyung Hee University, Yongin, Korea
⨯
Kelley Swanberg,

Affiliation Department of East-West Medicine, Graduate School of East-West Medical Science, Kyung Hee University, Yongin, Korea
⨯
Joo-Yeon Shin,

Affiliation Department of East-West Medicine, Graduate School of East-West Medical Science, Kyung Hee University, Yongin, Korea
⨯
Sang-Kyu Ha,

Affiliation Department of East-West Medicine, Graduate School of East-West Medical Science, Kyung Hee University, Yongin, Korea
⨯
Yoonju Cho,

Affiliation Department of Applied Korean Medicine, College of Oriental Medicine, Kyung Hee University, Seoul, Korea
⨯
Soo-Yong Bang,

Affiliation Department of East-West Medicine, Graduate School of East-West Medical Science, Kyung Hee University, Yongin, Korea
⨯
Jae-Hwan Lew,

Affiliation Department of East-West Medicine, Graduate School of East-West Medical Science, Kyung Hee University, Yongin, Korea
⨯
Seung-Hun Cho,

Affiliation Department of Neuropsychiatry, College of Oriental Medicine, Kyung Hee University, Seoul, Korea
⨯
Sungho Maeng

* E-mail: jethrot@hotmail.com

Affiliation Department of East-West Medicine, Graduate School of East-West Medical Science, Kyung Hee University, Yongin, Korea
⨯

Preclinical Evidence of Rapid-Onset Antidepressant-Like Effect in Radix Polygalae Extract

Im-Joon Shin,
Sung Un Son,
Hyunwoo Park,
Yoorim Kim,
Sung Hyun Park,
Kelley Swanberg,
Joo-Yeon Shin,
Sang-Kyu Ha,
Yoonju Cho,
Soo-Yong Bang

Published: February 10, 2014
https://doi.org/10.1371/journal.pone.0088617

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Antidepressants
Is the Subject Area "Antidepressants" applicable to this article?

Thanks for your feedback.
Distillation
Is the Subject Area "Distillation" applicable to this article?

Thanks for your feedback.
Mouse models
Is the Subject Area "Mouse models" applicable to this article?

Thanks for your feedback.
Phosphorylation
Is the Subject Area "Phosphorylation" applicable to this article?

Thanks for your feedback.
Hippocampus
Is the Subject Area "Hippocampus" applicable to this article?

Thanks for your feedback.
Depression
Is the Subject Area "Depression" applicable to this article?

Thanks for your feedback.
Mice
Is the Subject Area "Mice" applicable to this article?

Thanks for your feedback.
Antidepressant drug therapy
Is the Subject Area "Antidepressant drug therapy" applicable to this article?

Thanks for your feedback.