Essential Role of TEA Domain Transcription Factors in the Negative Regulation of the MYH 7 Gene by Thyroid Hormone and Its Receptors

Hiroyuki Iwaki; Shigekazu Sasaki; Akio Matsushita; Kenji Ohba; Hideyuki Matsunaga; Hiroko Misawa; Yutaka Oki; Keiko Ishizuka; Hirotoshi Nakamura; Takafumi Suda

doi:10.1371/journal.pone.0088610

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Open Access

Peer-reviewed

Research Article

Essential Role of TEA Domain Transcription Factors in the Negative Regulation of the MYH 7 Gene by Thyroid Hormone and Its Receptors

Hiroyuki Iwaki,

Current address: Division of Endocrinology, Department of Internal Medicine, Seirei Hamamatsu General Hospital, Hamamatsu, Shizuoka, Japan

Affiliation Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan
⨯
Shigekazu Sasaki ,

* E-mail: sasakis@hama-med.ac.jp

Affiliation Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan
⨯
Akio Matsushita,

Affiliation Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan
⨯
Kenji Ohba,

Affiliation Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan
⨯
Hideyuki Matsunaga,

Affiliation Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan
⨯
Hiroko Misawa,

Affiliation Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan
⨯
Yutaka Oki,

Affiliation Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan
⨯
Keiko Ishizuka,

Affiliation Department of Laboratory Medicine, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan
⨯
Hirotoshi Nakamura,

Affiliation Department of Internal Medicine, Kuma Hospital, Kobe, Hyogo, Japan
⨯
Takafumi Suda

Affiliation Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan
⨯

Essential Role of TEA Domain Transcription Factors in the Negative Regulation of the MYH 7 Gene by Thyroid Hormone and Its Receptors

Hiroyuki Iwaki,
Shigekazu Sasaki,
Akio Matsushita,
Kenji Ohba,
Hideyuki Matsunaga,
Hiroko Misawa,
Yutaka Oki,
Keiko Ishizuka,
Hirotoshi Nakamura,
Takafumi Suda

Published: April 29, 2014
https://doi.org/10.1371/journal.pone.0088610

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Gene regulation
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Transfection
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DNA transcription
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Transcription factors
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Plasmid construction
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Transactivation
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Gene expression
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Transcriptional control
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