Maternal Plasma Fetal DNA Fractions in Pregnancies with Low and High Risks for Fetal Chromosomal Aneuploidies

Irena Hudecova; Daljit Sahota; Macy M. S. Heung; Yongjie Jin; Wing S. Lee; Tak Y. Leung; Yuk Ming Dennis Lo; Rossa W.K. Chiu

doi:10.1371/journal.pone.0088484

Loading metrics

Open Access

Peer-reviewed

Research Article

Maternal Plasma Fetal DNA Fractions in Pregnancies with Low and High Risks for Fetal Chromosomal Aneuploidies

Irena Hudecova ,

Contributed equally to this work with: Irena Hudecova, Daljit Sahota

Affiliations Centre for Research into Circulating Fetal Nucleic Acids, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China, Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China
⨯
Daljit Sahota ,

Contributed equally to this work with: Irena Hudecova, Daljit Sahota

Affiliation Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China
⨯
Macy M. S. Heung,

Affiliations Centre for Research into Circulating Fetal Nucleic Acids, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China, Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China
⨯
Yongjie Jin,

Affiliations Centre for Research into Circulating Fetal Nucleic Acids, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China, Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China
⨯
Wing S. Lee,

Affiliations Centre for Research into Circulating Fetal Nucleic Acids, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China, Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China
⨯
Tak Y. Leung,

Affiliation Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China
⨯
Yuk Ming Dennis Lo,

Affiliations Centre for Research into Circulating Fetal Nucleic Acids, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China, Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China
⨯
Rossa W.K. Chiu

* E-mail: rossachiu@cuhk.edu.hk

Affiliations Centre for Research into Circulating Fetal Nucleic Acids, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China, Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China
⨯

Maternal Plasma Fetal DNA Fractions in Pregnancies with Low and High Risks for Fetal Chromosomal Aneuploidies

Irena Hudecova,
Daljit Sahota,
Macy M. S. Heung,
Yongjie Jin,
Wing S. Lee,
Tak Y. Leung,
Yuk Ming Dennis Lo,
Rossa W.K. Chiu

Published: February 28, 2014
https://doi.org/10.1371/journal.pone.0088484

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Pregnancy
Is the Subject Area "Pregnancy" applicable to this article?

Thanks for your feedback.
Medical risk factors
Is the Subject Area "Medical risk factors" applicable to this article?

Thanks for your feedback.
Aneuploidy
Is the Subject Area "Aneuploidy" applicable to this article?

Thanks for your feedback.
Management of high-risk pregnancies
Is the Subject Area "Management of high-risk pregnancies" applicable to this article?

Thanks for your feedback.
Fetuses
Is the Subject Area "Fetuses" applicable to this article?

Thanks for your feedback.
Y chromosomes
Is the Subject Area "Y chromosomes" applicable to this article?

Thanks for your feedback.
Blood plasma
Is the Subject Area "Blood plasma" applicable to this article?

Thanks for your feedback.
DNA sequencing
Is the Subject Area "DNA sequencing" applicable to this article?

Thanks for your feedback.