Alterations of Mass Density and 3D Osteocyte Lacunar Properties in Bisphosphonate-Related Osteonecrotic Human Jaw Bone, a Synchrotron µCT Study

Bernhard Hesse; Max Langer; Peter Varga; Alexandra Pacureanu; Pei Dong; Susanne Schrof; Nils Männicke; Heikki Suhonen; Cecile Olivier; Peter Maurer; Galateia J. Kazakia; Kay Raum; Francoise Peyrin

doi:10.1371/journal.pone.0088481

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Peer-reviewed

Research Article

Alterations of Mass Density and 3D Osteocyte Lacunar Properties in Bisphosphonate-Related Osteonecrotic Human Jaw Bone, a Synchrotron µCT Study

Bernhard Hesse,

Affiliations European Synchrotron Radiation Facility, Grenoble, France, Berlin-Brandenburg School for Regenerative Therapies & Julius Wolff Institut, Charité, Universitätsmedizin Berlin, Germany
⨯
Max Langer,

Affiliations European Synchrotron Radiation Facility, Grenoble, France, Université de Lyon, CREATIS, CNRS UMR5220, INSA-Lyon, Lyon, France
⨯
Peter Varga,

Affiliation Berlin-Brandenburg School for Regenerative Therapies & Julius Wolff Institut, Charité, Universitätsmedizin Berlin, Germany
⨯
Alexandra Pacureanu,

Affiliations European Synchrotron Radiation Facility, Grenoble, France, Université de Lyon, CREATIS, CNRS UMR5220, INSA-Lyon, Lyon, France, Centre for Image Analysis and Science for Life Laboratory, Uppsala University, Uppsala, Sweden
⨯
Pei Dong,

Affiliations European Synchrotron Radiation Facility, Grenoble, France, Université de Lyon, CREATIS, CNRS UMR5220, INSA-Lyon, Lyon, France
⨯
Susanne Schrof,

Affiliation Berlin-Brandenburg School for Regenerative Therapies & Julius Wolff Institut, Charité, Universitätsmedizin Berlin, Germany
⨯
Nils Männicke,

Affiliation Berlin-Brandenburg School for Regenerative Therapies & Julius Wolff Institut, Charité, Universitätsmedizin Berlin, Germany
⨯
Heikki Suhonen,

Affiliation European Synchrotron Radiation Facility, Grenoble, France
⨯
Cecile Olivier,

Affiliations European Synchrotron Radiation Facility, Grenoble, France, Université de Lyon, CREATIS, CNRS UMR5220, INSA-Lyon, Lyon, France
⨯
Peter Maurer,

Affiliation Klinik für Mund-, Kiefer- und Gesichtschirurgie, Klinikum Bremerhaven-Reinkenheide, Kiel, Germany
⨯
Galateia J. Kazakia,

Affiliation Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, California, United States of America
⨯
Kay Raum ,

Contributed equally to this work with: Kay Raum, Francoise Peyrin

Affiliation Berlin-Brandenburg School for Regenerative Therapies & Julius Wolff Institut, Charité, Universitätsmedizin Berlin, Germany
⨯
Francoise Peyrin

Contributed equally to this work with: Kay Raum, Francoise Peyrin

* E-mail: peyrin@esrf.fr

Affiliations European Synchrotron Radiation Facility, Grenoble, France, Université de Lyon, CREATIS, CNRS UMR5220, INSA-Lyon, Lyon, France
⨯

Alterations of Mass Density and 3D Osteocyte Lacunar Properties in Bisphosphonate-Related Osteonecrotic Human Jaw Bone, a Synchrotron µCT Study

Bernhard Hesse,
Max Langer,
Peter Varga,
Alexandra Pacureanu,
Pei Dong,
Susanne Schrof,
Nils Männicke,
Heikki Suhonen,
Cecile Olivier,
Peter Maurer

Published: February 21, 2014
https://doi.org/10.1371/journal.pone.0088481

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