Development and Validation of a Chemostat Gut Model To Study Both Planktonic and Biofilm Modes of Growth of Clostridium difficile and Human Microbiota

• Grace S. Crowther,

  Affiliation Leeds Institute of Biomedical and Clinical Sciences, Faculty of Medicine and Health, University of Leeds, Leeds, United Kingdom

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• Caroline H. Chilton,

  Affiliation Leeds Institute of Biomedical and Clinical Sciences, Faculty of Medicine and Health, University of Leeds, Leeds, United Kingdom

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• Sharie L. Todhunter,

  Affiliation Leeds Institute of Biomedical and Clinical Sciences, Faculty of Medicine and Health, University of Leeds, Leeds, United Kingdom

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• Scott Nicholson,

  Affiliation School of Science, University of West Scotland, Hamilton, United Kingdom

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• Jane Freeman,

  Affiliation Department of Microbiology, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom

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• Simon D. Baines,

  Affiliation School of Life and Medical Sciences, Department of Human and Environmental Sciences, University of Hertfordshire, Hatfield, United Kingdom

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• Mark H. Wilcox

  * E-mail: mark.wilcox@leedsth.nhs.uk

  Affiliations Leeds Institute of Biomedical and Clinical Sciences, Faculty of Medicine and Health, University of Leeds, Leeds, United Kingdom, Department of Microbiology, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom

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