Changes in Intestinal Glucocorticoid Sensitivity in Early Life Shape the Risk of Epithelial Barrier Defect in Maternal-Deprived Rats

Nabila Moussaoui; Viorica Braniste; Afifa Ait-Belgnaoui; Mélissa Gabanou; Soraya Sekkal; Maiwenn Olier; Vassilia Théodorou; Pascal G. P. Martin; Eric Houdeau

doi:10.1371/journal.pone.0088382

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Peer-reviewed

Research Article

Changes in Intestinal Glucocorticoid Sensitivity in Early Life Shape the Risk of Epithelial Barrier Defect in Maternal-Deprived Rats

Nabila Moussaoui,

Affiliations Intestinal Development, Xenobiotics & Immunotoxicology, Institut National de la Recherche Agronomique (INRA), Research Centre in Food Toxicology (Toxalim), Toulouse, France, Integrative Toxicology & Metabolism, INRA, Toxalim, Toulouse, France
⨯
Viorica Braniste,

Affiliation Intestinal Development, Xenobiotics & Immunotoxicology, Institut National de la Recherche Agronomique (INRA), Research Centre in Food Toxicology (Toxalim), Toulouse, France
⨯
Afifa Ait-Belgnaoui,

Affiliation Neurogastroenterology & Nutrition, INRA, Toxalim, Toulouse, France
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Mélissa Gabanou,

Affiliation Intestinal Development, Xenobiotics & Immunotoxicology, Institut National de la Recherche Agronomique (INRA), Research Centre in Food Toxicology (Toxalim), Toulouse, France
⨯
Soraya Sekkal,

Affiliation Neurogastroenterology & Nutrition, INRA, Toxalim, Toulouse, France
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Maiwenn Olier,

Affiliation Neurogastroenterology & Nutrition, INRA, Toxalim, Toulouse, France
⨯
Vassilia Théodorou,

Affiliation Neurogastroenterology & Nutrition, INRA, Toxalim, Toulouse, France
⨯
Pascal G. P. Martin,

Affiliations Integrative Toxicology & Metabolism, INRA, Toxalim, Toulouse, France, GeT-TRiX facility, INRA, Toxalim, Toulouse, France
⨯
Eric Houdeau

* E-mail: eric.houdeau@toulouse.inra.fr

Current address: Institut National de la Recherche Agronomique, Toxalim UMR1331, 180 chemin de Tournefeuille, BP 93173, 31027 Toulouse Cedex 3, France

Affiliation Intestinal Development, Xenobiotics & Immunotoxicology, Institut National de la Recherche Agronomique (INRA), Research Centre in Food Toxicology (Toxalim), Toulouse, France
⨯

Changes in Intestinal Glucocorticoid Sensitivity in Early Life Shape the Risk of Epithelial Barrier Defect in Maternal-Deprived Rats

Nabila Moussaoui,
Viorica Braniste,
Afifa Ait-Belgnaoui,
Mélissa Gabanou,
Soraya Sekkal,
Maiwenn Olier,
Vassilia Théodorou,
Pascal G. P. Martin,
Eric Houdeau

Published: February 20, 2014
https://doi.org/10.1371/journal.pone.0088382

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