Activated α2-Macroglobulin Binding to Cell Surface GRP78 Induces T-Loop Phosphorylation of Akt1 by PDK1 in Association with Raptor

Open Access

Peer-reviewed

Research Article

Activated α₂-Macroglobulin Binding to Cell Surface GRP78 Induces T-Loop Phosphorylation of Akt1 by PDK1 in Association with Raptor

Uma Kant Misra,

Affiliation Department of Pathology, Duke University Medical Center, Durham, North Carolina, United States of America
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Salvatore Vincent Pizzo

* E-mail: salvatore.pizzo@duke.edu

Affiliation Department of Pathology, Duke University Medical Center, Durham, North Carolina, United States of America
⨯

Raptors
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Phosphorylation
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Immunoprecipitation
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Prostate cancer
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RNA interference
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Insulin
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Cell membranes
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Co-immunoprecipitation
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