Prednisolone Attenuates Improvement of Cardiac and Skeletal Contractile Function and Histopathology by Lisinopril and Spironolactone in the mdx Mouse Model of Duchenne Muscular Dystrophy

Paul M. L. Janssen; Jason D. Murray; Kevin E. Schill; Neha Rastogi; Eric J. Schultz; Tam Tran; Subha V. Raman; Jill A. Rafael-Fortney

doi:10.1371/journal.pone.0088360

Loading metrics

Open Access

Peer-reviewed

Research Article

Prednisolone Attenuates Improvement of Cardiac and Skeletal Contractile Function and Histopathology by Lisinopril and Spironolactone in the mdx Mouse Model of Duchenne Muscular Dystrophy

Paul M. L. Janssen ,

Contributed equally to this work with: Paul M. L. Janssen, Jill A. Rafael-Fortney

* E-mail: janssen.10@osu.edu (PJ); rafael-fortney.1@osu.edu (JR-F)

Affiliations Department of Physiology and Cell Biology, The Ohio State University, Columbus, Ohio, United States of America, Dorothy M. Davis Heart & Lung Institute, The Ohio State University, Columbus, Ohio, United States of America
⨯
Jason D. Murray,

Affiliation Department of Physiology and Cell Biology, The Ohio State University, Columbus, Ohio, United States of America
⨯
Kevin E. Schill,

Affiliation Department of Molecular and Cellular Biochemistry, The Ohio State University, Columbus, Ohio, United States of America
⨯
Neha Rastogi,

Affiliation Department of Physiology and Cell Biology, The Ohio State University, Columbus, Ohio, United States of America
⨯
Eric J. Schultz,

Affiliation Department of Molecular and Cellular Biochemistry, The Ohio State University, Columbus, Ohio, United States of America
⨯
Tam Tran,

Affiliation Division of Cardiovascular Medicine, The Ohio State University, Columbus, Ohio, United States of America
⨯
Subha V. Raman,

Affiliations Division of Cardiovascular Medicine, The Ohio State University, Columbus, Ohio, United States of America, Dorothy M. Davis Heart & Lung Institute, The Ohio State University, Columbus, Ohio, United States of America
⨯
Jill A. Rafael-Fortney

Contributed equally to this work with: Paul M. L. Janssen, Jill A. Rafael-Fortney

* E-mail: janssen.10@osu.edu (PJ); rafael-fortney.1@osu.edu (JR-F)

Affiliations Department of Molecular and Cellular Biochemistry, The Ohio State University, Columbus, Ohio, United States of America, Dorothy M. Davis Heart & Lung Institute, The Ohio State University, Columbus, Ohio, United States of America
⨯

Prednisolone Attenuates Improvement of Cardiac and Skeletal Contractile Function and Histopathology by Lisinopril and Spironolactone in the mdx Mouse Model of Duchenne Muscular Dystrophy

Paul M. L. Janssen,
Jason D. Murray,
Kevin E. Schill,
Neha Rastogi,
Eric J. Schultz,
Tam Tran,
Subha V. Raman,
Jill A. Rafael-Fortney

Published: February 13, 2014
https://doi.org/10.1371/journal.pone.0088360

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

ACE inhibitor therapy
Is the Subject Area "ACE inhibitor therapy" applicable to this article?

Thanks for your feedback.
Mouse models
Is the Subject Area "Mouse models" applicable to this article?

Thanks for your feedback.
Cardiac muscles
Is the Subject Area "Cardiac muscles" applicable to this article?

Thanks for your feedback.
Skeletal muscles
Is the Subject Area "Skeletal muscles" applicable to this article?

Thanks for your feedback.
Heart
Is the Subject Area "Heart" applicable to this article?

Thanks for your feedback.
Muscle contraction
Is the Subject Area "Muscle contraction" applicable to this article?

Thanks for your feedback.
Duchenne muscular dystrophy
Is the Subject Area "Duchenne muscular dystrophy" applicable to this article?

Thanks for your feedback.
Body weight
Is the Subject Area "Body weight" applicable to this article?

Thanks for your feedback.