Combination of 1H NMR- and GC-MS-Based Metabonomics to Study on the Toxicity of Coptidis Rhizome in Rats

Open Access

Peer-reviewed

Research Article

Combination of ¹H NMR- and GC-MS-Based Metabonomics to Study on the Toxicity of Coptidis Rhizome in Rats

Yuting Zhou ,

Contributed equally to this work with: Yuting Zhou, Qiongfeng Liao

Affiliation School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, People's Republic of China
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Qiongfeng Liao ,

Contributed equally to this work with: Yuting Zhou, Qiongfeng Liao

Affiliation School of Chinese Materia Medica, Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China
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Manna Lin,

Affiliations School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, People's Republic of China, School of Chinese Materia Medica, Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China
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Xuejiao Deng,

Affiliation School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, People's Republic of China
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Peiting Zhang,

Affiliation School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, People's Republic of China
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Meicun Yao,

Affiliation School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, People's Republic of China
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Lei Zhang,

Affiliation School of Chinese Materia Medica, Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China
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Zhiyong Xie

* E-mail: xiezy2074@yahoo.com

Affiliation School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, People's Republic of China
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Metabolites
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Urine
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Diarrhea
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Gas chromatography-mass spectrometry
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Toxicity
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Gut bacteria
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NMR spectroscopy
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Biomarkers
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