A Comparative Study of N-glycolylneuraminic Acid (Neu5Gc) and Cytotoxic T Cell (CT) Carbohydrate Expression in Normal and Dystrophin-Deficient Dog and Human Skeletal Muscle

Paul T. Martin; Bethannie Golden; Jonathan Okerblom; Marybeth Camboni; Kumaran Chandrasekharan; Rui Xu; Ajit Varki; Kevin M. Flanigan; Joe N. Kornegay

doi:10.1371/journal.pone.0088226

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Research Article

A Comparative Study of N-glycolylneuraminic Acid (Neu5Gc) and Cytotoxic T Cell (CT) Carbohydrate Expression in Normal and Dystrophin-Deficient Dog and Human Skeletal Muscle

Paul T. Martin ,

* E-mail: Paul.Martin@nationwidechildrens.org

Affiliations Center for Gene Therapy, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, United States of America, Department of Pediatrics, The Ohio State University College of Medicine, Columbus, Ohio, United States of America, Department of Physiology and Cell Biology, The Ohio State University College of Medicine, Columbus, Ohio, United States of America
⨯
Bethannie Golden,

Affiliation Center for Gene Therapy, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, United States of America
⨯
Jonathan Okerblom,

Affiliation Departments of Medicine and Cellular and Molecular Medicine, University of California, San Diego, La Jolla, California, United States of America
⨯
Marybeth Camboni,

Affiliation Center for Gene Therapy, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, United States of America
⨯
Kumaran Chandrasekharan,

Affiliation Center for Gene Therapy, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, United States of America
⨯
Rui Xu,

Affiliation Center for Gene Therapy, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, United States of America
⨯
Ajit Varki,

Affiliation Departments of Medicine and Cellular and Molecular Medicine, University of California, San Diego, La Jolla, California, United States of America
⨯
Kevin M. Flanigan,

Affiliations Center for Gene Therapy, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, United States of America, Department of Pediatrics, The Ohio State University College of Medicine, Columbus, Ohio, United States of America
⨯
Joe N. Kornegay

Affiliation Department of Veterinary Integrative Biosciences, Texas A&M University, College Station, Texas, United States of America
⨯

A Comparative Study of N-glycolylneuraminic Acid (Neu5Gc) and Cytotoxic T Cell (CT) Carbohydrate Expression in Normal and Dystrophin-Deficient Dog and Human Skeletal Muscle

Paul T. Martin,
Bethannie Golden,
Jonathan Okerblom,
Marybeth Camboni,
Kumaran Chandrasekharan,
Rui Xu,
Ajit Varki,
Kevin M. Flanigan,
Joe N. Kornegay

Published: February 5, 2014
https://doi.org/10.1371/journal.pone.0088226

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