A Novel Pathway Links Oxidative Stress to Loss of Insulin Growth Factor-2 (IGF2) Imprinting through NF-κB Activation

Bing Yang; Jennifer Wagner; Nathan Damaschke; Tianyu Yao; Shelly M. Wuerzberger-Davis; Moon-Hee Lee; John Svaren; Shigeki Miyamoto; David F. Jarrard

doi:10.1371/journal.pone.0088052

Loading metrics

Open Access

Peer-reviewed

Research Article

A Novel Pathway Links Oxidative Stress to Loss of Insulin Growth Factor-2 (IGF2) Imprinting through NF-κB Activation

Bing Yang,

Affiliation Department of Urology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America
⨯
Jennifer Wagner,

Affiliation Department of Urology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America
⨯
Nathan Damaschke,

Affiliation Department of Urology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America
⨯
Tianyu Yao,

Affiliation Department of Urology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America
⨯
Shelly M. Wuerzberger-Davis,

Affiliation Department of Oncology, McArdle Laboratory for Cancer Research, University of Wisconsin, Madison, Wisconsin, United States of America
⨯
Moon-Hee Lee,

Affiliation Department of Oncology, McArdle Laboratory for Cancer Research, University of Wisconsin, Madison, Wisconsin, United States of America
⨯
John Svaren,

Affiliation Comparative Biosciences, University of Wisconsin, Madison, Wisconsin, United States of America
⨯
Shigeki Miyamoto,

Affiliations Department of Oncology, McArdle Laboratory for Cancer Research, University of Wisconsin, Madison, Wisconsin, United States of America, University of Wisconsin Carbone Comprehensive Cancer Center, Madison, Wisconsin, United States of America
⨯
David F. Jarrard

* E-mail: jarrard@urology.wisc.edu

Affiliations Department of Urology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America, University of Wisconsin Carbone Comprehensive Cancer Center, Madison, Wisconsin, United States of America, Environmental and Molecular Toxicology, University of Wisconsin, Madison, Wisconsin, United States of America
⨯

A Novel Pathway Links Oxidative Stress to Loss of Insulin Growth Factor-2 (IGF2) Imprinting through NF-κB Activation

Bing Yang,
Jennifer Wagner,
Nathan Damaschke,
Tianyu Yao,
Shelly M. Wuerzberger-Davis,
Moon-Hee Lee,
John Svaren,
Shigeki Miyamoto,
David F. Jarrard

Published: February 18, 2014
https://doi.org/10.1371/journal.pone.0088052

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Transcription factors
Is the Subject Area "Transcription factors" applicable to this article?

Thanks for your feedback.
Prostate gland
Is the Subject Area "Prostate gland" applicable to this article?

Thanks for your feedback.
Oxidative stress
Is the Subject Area "Oxidative stress" applicable to this article?

Thanks for your feedback.
DNA methylation
Is the Subject Area "DNA methylation" applicable to this article?

Thanks for your feedback.
Prostate cancer
Is the Subject Area "Prostate cancer" applicable to this article?

Thanks for your feedback.
Mouse models
Is the Subject Area "Mouse models" applicable to this article?

Thanks for your feedback.
Aging and cancer
Is the Subject Area "Aging and cancer" applicable to this article?

Thanks for your feedback.
Epigenetics
Is the Subject Area "Epigenetics" applicable to this article?

Thanks for your feedback.