Development of a Human Dihydroorotate Dehydrogenase (hDHODH) Pharma-Similarity Index Approach with Scaffold-Hopping Strategy for the Design of Novel Potential Inhibitors

• Kuei-Chung Shih ,

  * E-mail: kcshih0307@gmail.com (KCS); cytang@pu.edu.tw (CYT)

  Affiliation Department of Computer Science, National Tsing Hua University, Hsinchu, Taiwan

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• Chi-Ching Lee,

  Affiliation Bioinformatics Center, Chang Gung University, Taoyuan, Taiwan

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• Chi-Neu Tsai,

  Affiliation Graduate Institute of Chang-Gung Medical Science, Chang-Gung University, Taoyuan, Taiwan

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• Yu-Shan Lin,

  Affiliation Department of Computer Science, National Tsing Hua University, Hsinchu, Taiwan

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• Chuan-Yi Tang

  * E-mail: kcshih0307@gmail.com (KCS); cytang@pu.edu.tw (CYT)

  Affiliations Department of Computer Science, National Tsing Hua University, Hsinchu, Taiwan, Department of Computer Science and Information Engineering, Providence University, Taichung, Taiwan

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