Enhanced Virus-Specific CD8+ T Cell Responses by Listeria monocytogenes-Infected Dendritic Cells in the Context of Tim-3 Blockade

Cheng J. Ma; Jun P. Ren; Guang Y. Li; Xiao Y. Wu; Dirk G. Brockstedt; Peter Lauer; Jonathan P. Moorman; Zhi Q. Yao

doi:10.1371/journal.pone.0087821

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Open Access

Peer-reviewed

Research Article

Enhanced Virus-Specific CD8⁺ T Cell Responses by Listeria monocytogenes-Infected Dendritic Cells in the Context of Tim-3 Blockade

Cheng J. Ma,

Current address: Center of Infectious Diseases, Beijing Ditan Hospital Captial Medical University, Beijing, China

Affiliation Department of Internal Medicine, Division of Infectious Diseases, Quillen College of Medicine, East Tennessee State University, Johnson City, Tennessee, United States of America
⨯
Jun P. Ren,

Affiliation Department of Internal Medicine, Division of Infectious Diseases, Quillen College of Medicine, East Tennessee State University, Johnson City, Tennessee, United States of America
⨯
Guang Y. Li,

Affiliation Department of Internal Medicine, Division of Infectious Diseases, Quillen College of Medicine, East Tennessee State University, Johnson City, Tennessee, United States of America
⨯
Xiao Y. Wu,

Affiliation Department of Internal Medicine, Division of Infectious Diseases, Quillen College of Medicine, East Tennessee State University, Johnson City, Tennessee, United States of America
⨯
Dirk G. Brockstedt,

Affiliation Aduro BioTech, Inc. Berkeley, California, United States of America
⨯
Peter Lauer,

Affiliation Aduro BioTech, Inc. Berkeley, California, United States of America
⨯
Jonathan P. Moorman,

Affiliations Hepatitis (HCV/HIV) Program, Department of Veterans Affairs, James H. Quillen VA Medical Center, Johnson City, Tennessee, United States of America, Department of Internal Medicine, Division of Infectious Diseases, Quillen College of Medicine, East Tennessee State University, Johnson City, Tennessee, United States of America
⨯
Zhi Q. Yao

* E-mail: Yao@etsu.edu

Affiliations Hepatitis (HCV/HIV) Program, Department of Veterans Affairs, James H. Quillen VA Medical Center, Johnson City, Tennessee, United States of America, Department of Internal Medicine, Division of Infectious Diseases, Quillen College of Medicine, East Tennessee State University, Johnson City, Tennessee, United States of America
⨯

Enhanced Virus-Specific CD8⁺ T Cell Responses by Listeria monocytogenes-Infected Dendritic Cells in the Context of Tim-3 Blockade

Cheng J. Ma,
Jun P. Ren,
Guang Y. Li,
Xiao Y. Wu,
Dirk G. Brockstedt,
Peter Lauer,
Jonathan P. Moorman,
Zhi Q. Yao

Published: January 31, 2014
https://doi.org/10.1371/journal.pone.0087821

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