Negative Auto-Regulation of Myostatin Expression is Mediated by Smad3 and MicroRNA-27

Craig McFarlane; Anuradha Vajjala; Harikumar Arigela; Sudarsanareddy Lokireddy; XiaoJia Ge; Sabeera Bonala; Ravikumar Manickam; Ravi Kambadur; Mridula Sharma

doi:10.1371/journal.pone.0087687

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Open Access

Peer-reviewed

Research Article

Negative Auto-Regulation of Myostatin Expression is Mediated by Smad3 and MicroRNA-27

Craig McFarlane ,

¶CM and MS are joint senior authors on this work.

Affiliation Singapore Institute for Clinical Sciences, Agency for Science, Technology and Research, Singapore, Singapore
⨯
Anuradha Vajjala ,

Contributed equally to this work with: Anuradha Vajjala, Harikumar Arigela

Affiliation School of Biological Sciences, Nanyang Technological University, Singapore, Singapore
⨯
Harikumar Arigela ,

Contributed equally to this work with: Anuradha Vajjala, Harikumar Arigela

Current address: Department of Genetics, The Hebrew University of Jerusalem, Jerusalem, Israel

Affiliation School of Biological Sciences, Nanyang Technological University, Singapore, Singapore
⨯
Sudarsanareddy Lokireddy,

Current address: Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, United States of America

Affiliation School of Biological Sciences, Nanyang Technological University, Singapore, Singapore
⨯
XiaoJia Ge,

Affiliation School of Biological Sciences, Nanyang Technological University, Singapore, Singapore
⨯
Sabeera Bonala,

Affiliation School of Biological Sciences, Nanyang Technological University, Singapore, Singapore
⨯
Ravikumar Manickam,

Affiliation School of Biological Sciences, Nanyang Technological University, Singapore, Singapore
⨯
Ravi Kambadur,

Affiliations Singapore Institute for Clinical Sciences, Agency for Science, Technology and Research, Singapore, Singapore, School of Biological Sciences, Nanyang Technological University, Singapore, Singapore
⨯
Mridula Sharma

* E-mail: bchmridu@nus.edu.sg

¶CM and MS are joint senior authors on this work.

Affiliation Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
⨯

Negative Auto-Regulation of Myostatin Expression is Mediated by Smad3 and MicroRNA-27

Craig McFarlane,
Anuradha Vajjala,
Harikumar Arigela,
Sudarsanareddy Lokireddy,
XiaoJia Ge,
Sabeera Bonala,
Ravikumar Manickam,
Ravi Kambadur,
Mridula Sharma

Published: January 31, 2014
https://doi.org/10.1371/journal.pone.0087687

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23 May 2014
02:58 GMT
Most Recent

Correction Posted by Sharmam on 23 May 2014 at 02:58 GMT

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