Preclinical Evaluation of the Novel, Orally Bioavailable Selective Inhibitor of Nuclear Export (SINE) KPT-335 in Spontaneous Canine Cancer: Results of a Phase I Study

• Cheryl A. London ,

  * E-mail: Cheryl.London@cvm.osu.edu

  Affiliation Departments of Veterinary Biosciences and Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, Columbus, Ohio, United States of America

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• Luis Feo Bernabe,

  Affiliation Departments of Veterinary Biosciences and Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, Columbus, Ohio, United States of America

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• Sandra Barnard,

  Affiliation Departments of Veterinary Biosciences and Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, Columbus, Ohio, United States of America

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• William C. Kisseberth,

  Affiliation Departments of Veterinary Biosciences and Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, Columbus, Ohio, United States of America

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• Antonella Borgatti,

  Affiliation Department of Veterinary Clinical Sciences and Masonic Cancer Center, University of Minnesota, Minneapolis/St. Paul, Minnesota, United States of America

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• Mike Henson,

  Affiliation Department of Veterinary Clinical Sciences and Masonic Cancer Center, University of Minnesota, Minneapolis/St. Paul, Minnesota, United States of America

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• Heather Wilson,

  Affiliation Department of Small Animal Clinical Sciences, Texas A&M University, College Station, Texas, United States of America

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• Kiersten Jensen,

  Affiliation Department of Veterinary Clinical Sciences and Masonic Cancer Center, University of Minnesota, Minneapolis/St. Paul, Minnesota, United States of America

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• Daisuke Ito,

  Affiliation Department of Veterinary Clinical Sciences and Masonic Cancer Center, University of Minnesota, Minneapolis/St. Paul, Minnesota, United States of America

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• Jaime F. Modiano,

  Affiliation Department of Veterinary Clinical Sciences and Masonic Cancer Center, University of Minnesota, Minneapolis/St. Paul, Minnesota, United States of America

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• Misty D. Bear,

  Affiliation Departments of Veterinary Biosciences and Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, Columbus, Ohio, United States of America

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• Michael L. Pennell,

  Affiliation Division of Biostatistics, College of Public Health, The Ohio State University, Columbus, Ohio, United States of America

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• Jean-Richard Saint-Martin,

  Affiliation Karyopharm Therapeutics, Natick, Massachusetts, United States of America

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• Dilara McCauley,

  Affiliation Karyopharm Therapeutics, Natick, Massachusetts, United States of America

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• Michael Kauffman,

  Affiliation Karyopharm Therapeutics, Natick, Massachusetts, United States of America

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•  [ ... ],
• Sharon Shacham

  Affiliation Karyopharm Therapeutics, Natick, Massachusetts, United States of America

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